783-88-0Relevant academic research and scientific papers
Biomimetic aerobic oxidation of amino alcohols to lactams
Babu, Beneesh P.,Endo, Yoshinori,Baeckvall, Jan-E.
supporting information, p. 11524 - 11527,4 (2012/12/11)
The right path: N-Protected amino alcohols undergo aerobic and biomimetic oxidation to the corresponding lactams in the presence of a ruthenium catalyst and a combination of electron-transfer mediators under air (see scheme). The reaction was used for the synthesis of five-, six-, and seven-, membered lactams and showed good tolerance to a number of N-protecting groups. Copyright
α-Amidation of cyclic ethers catalyzed by simple copper salt and a mild and efficient preparation method for α,ω-amino alcohols
He, Ling,Yu, Jing,Zhang, Ji,Yu, Xiao-Qi
, p. 2277 - 2280 (2008/02/04)
Copper(II) trifluoromethanesulfonate catalyzed the amidation of cyclic ethers with iminoiodanes under mild conditions (CH2Cl2, 40°C) with good yields (up to 86% based on 97% conversion) and selectivity (only α-amino products were fou
N-acyldipeptides, processes for the preparation thereof and pharmaceutical compositions containing the same
-
, (2008/06/13)
N-acyldipeptides of formula I STR1 wherein R represents a rest of formula STR2 and R4, Y, m, n and Z have the meaning as defined in the description, R1 represents hydrogen, a 1-10 C. alkyl, an optionally substituted methyl or benzyl,
Synthesis of polyammonium macrocycles with pendant chains
Gu, Kun-Jian,Bowman-James, Kristin
, p. 1977 - 1980 (2007/10/02)
A facile route is described for the synthesis of polyazaoxamacrocycles with pendant chains that is applicable for the preparation of a variety of macrocycles of differing ring size and heteroatom substitution.
An Alternative Synthesis of Cyclic Aza Compounds
Boerjesson, L.,Welch, C. J.
, p. 621 - 626 (2007/10/02)
A series of cyclic mono-, di- and poly-aza compounds has been synthesised in moderate to good yields by reaction of p-toluenesulfonamide and either α,ω-ditosylates or α,ω-dichlorides.
STRATEGY FOR THE SYNTHESIS OF UNSYMMETRICAL N-SUBSTITUTED POLYAZAMACROCYCLES
Gu, Kunjian,Mertes, Kristin Bowman,Mertes, Mathias P.
, p. 1323 - 1326 (2007/10/02)
A covergent route is described for the preparation of unsymmetrical N-substituted polyammonium macrocycles that is potentially applicable for the synthesis of a wide variety of macrocycles of differing ring size and heteroatom substitution.
Lipophilic Cage Ligands Containing Two Tightly Connected 1,7-Dioxa-4,10-diazacyclododecane Rings: Synthesis and X-ray Structure of a Sodium Perchlorate Complex
Anelli, Pier Lucio,Montanari, Fernando,Quici, Silvio,Ciani, Gianfranco,Sironi, Angelo
, p. 5292 - 5298 (2007/10/02)
Sodium perchlorate complexes 2 of lipophilic macrotricyclic receptors 1 were obtained in high yield by following a synthetic route in which sodium cation acts as the templating agent in the last step.Complexes with several inorganic salts were directly prepared from the free ligands 1, obtained by decomplexation of 2, or via anionic exchange from the complexes 2.Extraction data of alkali halides under two-phase conditions (H2O-CHCl3) with ligand 1a showed a cation extraction selectivity order Na+ >> K+ > Li+.Under liquid-liquid two-phase conditions, ligands 1 proved to be effective phase-transfer catalysts in hydroxide ion initiated carbanion formation from very weak carbon acids.The sodium complex 2a was crystallographically characterized.The sodium cation is in a nonsymmetric cubic environment of four oxygen (Na O 2.46 Angstroem) and four nitrogen (Na N 2.79 Angstroem) atoms.
