78349-02-7

Upstream product

• 13307-75-0 (phenylthio)methyllithium 
• 98-86-2 acetophenone 
• 17873-08-4 (phenylsulfanylmethyl)trimethylsilane 
• 108-98-5 thiophenol 
• 98-83-9 isopropenylbenzene 
• 52322-54-0 2-(phenylthio)benzo[d]isothiazol-3(2H)-one 1,1-dioxide 
• 591-51-5 phenyllithium 
• 2243-53-0 styrylacetic acid 
• 121086-93-9 Trimethyl-(1-methyl-1-phenyl-2-phenylsulfanyl-ethoxy)-silane 

Relevant academic research and scientific papers

Solvent-mediated switching between oxidative addition and addition-oxidation: Access to β-hydroxysulfides and β-arylsulfones by the addition of thiols to olefins in the presence of Oxone

The reaction between aryl olefins and thiols in the presence of Oxone in toluene-water (9:1, v/v) affords β-hydroxy-2-arylethyl aryl sulfides smoothly by the interception of intermediary thiyl radicals with aryl olefins; the former are generated by the ox

Aerial dioxygen activation: Vs. thiol-ene click reaction within a system

Markovnikov or anti-Markovnikov selective thiol-ene click (TEC) reactions and the synthesis of β-hydroxysulfides via aerial dioxygen activation are prevalent C-S bond forming reactions of styrenes and thiophenols. Herein, by choosing appropriate environme

Enantioselective, Lewis Base-Catalyzed Carbosulfenylation of Alkenylboronates by 1,2-Boronate Migration

A catalytic, enantioselective method for the preparation of chiral, non-racemic, alkylboronic esters bearing two vicinal stereogenic centers is described. The reaction proceeds via a 1,2-migration of a zwitterionic thiiranium-boronate complex to give excl

Stereoselective synthesis of 3,4-di-substituted mercaptolactones via photoredox-catalyzed radical addition of thiophenols

A visible light mediated radical addition of thiophenols on 4-phenylbut-3-enoic acids to give diastereoselective synthesis of 3,4-disubstituted γ-lactones is reported. The reaction precludes the conventional prerequisite of conjugate addition. Furthermore, the lactones were successfully utilized in the synthesis of γ-ketoamides.

Air oxidative radical hydroxysulfurization of styrenes leading to β-hydroxysulfides

Air oxidative radical hydroxysulfurization of styrenes initiated by 0.5 mol % of tert-butyl hydroperoxide with arylthiols is described, and a new type of difunctionalization of alkenes was achieved.

NOVEL ARYLTHIOMETHYLATION OF CARBONYL COMPOUNDS USING ARYLTHIOMETHYLTRIMETHYLSILANES CATALYZED BY FLUORIDE IONS. NEW ROUTE TO β-HYDROXYARYLSULFIDES

Arylthiomethyltrimethylsilanes are good and mild nucleophilic reagents for introducing arylthiomethyl groups into carbonyl compounds promoted by tetra-n-butylammonium fluoride to give the corresponding β-hydroxyarylsulfides in fairly good yields.

FLUORIDE ION INDUCED REACTION OF PHENYLTHIOMETHYLTRIMETHYLSILANE (1) WITH ALDEHYDES AND KETONES: A SIMPLE PROCEDURE FOR THE FORMATION OF β-HYDROXYPHENYLSULPHIDES

The tetra n-butylammonium fluoride (TBAF) initiated reaction of phenylthiomethyltrimethylsilane (1) with aldehydes and ketones is reported. β-Hydroxy-phenylsulphides are formed in good yields even with ketones that contain enolizable protons.In contrast,

Selectivities in the Reactions of Alkyl-, Aryl- and Heterosubstituted Organotitanium Compounds

Solutions of the title compounds R-Ti(OR')3 (1) are generally available from organolithium (or magnesium) derivatives according to equation 1.It is shown (table 1) that some heterosubstituted organotitanium compounds are more stable thermally than their lithium counterparts.The reagents 1 are highly selective carbonylophiles (Tables 1 and 2), their reactivity can be modified by variation of the R'O-group (Table 3) and with the chiral (S)-2-methyl-1-butoxy group an enantioselective addition can be achieved.