784-50-9

Basic information

• Product Name: 9-Fluorenone-2-carboxylic acid
• Synonyms: 9-Oxo-2-fluorenecarboxyic Acid;9-FLUOROENONE-2-CARBOXYLIC ACID;9-Fluorenone-2-carboxylic acid,97%;9-Fluorenone-2-carboxylic acid,9-Oxo-2-fluorenecarboxylic acid;2-Carboxyfluoren-9-one;NSC 113321;NSC 81258;4-oxo-1-(pyridin-4-yl)cyclohexanecarbonitrile
• CAS NO: 784-50-9
• Molecular Formula: C₁₄H₈O₃
• Molecular Weight: 224.21
• EINECS: 212-317-3
• Product Categories: Fluorene Derivatives;Fluorenes, Flurenones;Carboxylic Acids;Fluorescent Labels and Indicators;Fluorenes & Fluorenones;Fluorenones;Fluorescent Labels & Indicators;Carboxylic Acids;Fused Ring Systems;Building Blocks;C13 to C42+;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks
• Mol File: 784-50-9.mol
• Article Data: 17

Chemical Properties

• Melting Point: >300 °C(lit.)
• Boiling Point: 325.61°C (rough estimate)
• Flash Point: 256.1 °C
• Appearance: Yellow/Fine Powder
• Density: 1.2337 (rough estimate)
• Vapor Pressure: 6.9E-10mmHg at 25°C
• Refractive Index: 1.5400 (estimate)
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 3.85±0.20(Predicted)
• CAS DataBase Reference: 9-Fluorenone-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 9-Fluorenone-2-carboxylic acid(784-50-9)
• EPA Substance Registry System: 9-Fluorenone-2-carboxylic acid(784-50-9)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 784-50-9(Hazardous Substances Data)

Usage

Chemical Properties

yellow fine powder

Uses

9-Fluorenone-2-carboxylic Acid (cas# 784-50-9) is a compound useful in organic synthesis.

Synthesis Reference(s)

Journal of the American Chemical Society, 70, p. 3958, 1948 DOI: 10.1021/ja01191a530Organic Syntheses, Coll. Vol. 3, p. 420, 1955

InChI:InChI=1/C14H8O3/c15-13-11-4-2-1-3-9(11)10-6-5-8(14(16)17)7-12(10)13/h1-7H,(H,16,17)/p-1

Upstream product

• 1430-97-3 2-methyl-9H-fluorene 
• 781-73-7 1-(9H-fluoren-2-yl)ethanone 
• 606-80-4 (1,1'-biphenyl)-2,4'-dicarboxylic acid 
• 64-19-7 acetic acid 
• 65007-01-4 1-(9H-fluorene-2-yl)propan-1-one 
• 607-57-8 2-nitro-9H-fluorene 
• 3096-52-4 2-nitro-9H-fluoren-9-one 
• 3096-57-9 2-amino-9-fluorenone 
• 3096-44-4 9H-fluorene-9-oxo-2-carbossamide 
• 3096-46-6 2-iodofluorenone 
• 106-42-3 para-xylene 
• 86-73-7 9H-fluorene 
• 65814-13-3 fluorenone 2,6-dimethylphenylhydrazone 
• 857234-88-9 1-fluoren-2-yl-2-methyl-propan-1-one 

Downstream Products

• 39180-42-2 2-(9-oxofluorenyl)carbonyl chloride 
• 1372415-93-4 C₂₅H₂₄O₆S 
• 876762-47-9 C₂₁H₂₁NO₂ 
• 119034-65-0 1-(9-oxo-2-fluorenylcarbonyl)-4-(3,4,5-trimethoxybenzyl)piperazine 
• 1430-97-3 2-methyl-9H-fluorene 
• 877667-26-0 3-(3-(trifluoromethyl)diazirin-3-yl)phenyl-9-oxo-9H-fluorene-2-carboxylate 

Relevant articles and documents

A new technique to prepare 9-oxofluorene-2-carboxylic acid

9-Oxofluorene-2-carboxylic acid has been obtained with a yield as high as 98.5%, following a new procedure with easy product extraction, based on the reaction of 2-acetylfluorene with sodium dichromate in acetic acid.

With Wnt signal path to inhibit the active heterocyclic compounds (by machine translation)

The invention relates to a signal path with Wnt inhibiting activity of a heterocyclic compound, including the compound and its pharmaceutically acceptable salt, various isotope, various isomers or various crystal structure, having the general formula I of the structure shown in: the invention relates to a compound and its joint application composition can effectively inhibit the Wnt signal path, can be used for the treatment or prevention of a disorder associated with a Wnt signal path. (by machine translation)

Polymeric Reagents Comprising a Terminal Vinylic Group and Conjugates Formed Therefrom

The present invention provides conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates. Methods of making polymeric reagents and conjugates, as well as methods for administering conjugates and compositions, are also provided.