784193-07-3

Upstream product

• 99-91-2 para-chloroacetophenone 
• 95-92-1 oxalic acid diethyl ester 
• 4039-32-1 lithium hexamethyldisilazane 

Downstream Products

• 1056965-70-8 4-(4-chlorophenyl)-2-[(2-chlorophenyl)hydrazono]-3-nitroso-4-oxobutyric acid ethyl ester 
• 1609483-18-2 ethyl 5-(4-chlorophenyl)-1-(4-(2,4-dichlorophenyl)thiazol-2-yl)-1H-pyrazole-3-carboxylate 
• 1609483-19-3 ethyl 5-(4-chlorophenyl)-1-(5-methyl-4-phenylthiazol-2-yl)-1H-pyrazole-3-carboxylate 
• 1609483-17-1 ethyl 5-(4-chlorophenyl)-1-(4-(4-chlorophenyl)thiazol-2-yl)-1H-pyrazole-3-carboxylate 
• 1609483-03-5 ethyl 5-(4-chlorophenyl)-1-(4-phenylthiazol-2-yl)-1H-pyrazole-3-carboxylate 
• 851728-99-9 1-(2-chlorophenyl)-5-(4-chlorophenyl)-1H-pyrazole-3-carboxylic acid 

Relevant academic research and scientific papers

An efficient one-pot synthesis of aryl-substituted 1-(thiazol-2-yl)-1H- pyrazole-3-carboxylates via a hantzsch synthesis-knorr reaction sequence

The treatment of α-bromoalkyl aryl ketones and 2-(propan-2-ylidene) hydrazine carbothioamide afforded 4-aryl-2-(2-(propan-2-ylidene)hydrazinyl) thiazoles via a Hantzsch-thiazole synthesis, which reacted with 4-aryl-2,4-diketoesters via a sequential Knorr-

Imidazol-4-one and Imidazole-4-thione Compounds

Imidazol-4-one or imidazole-4-thione compounds of formula (I): wherein X, R1, R2, R3, R4, R5, and R6 are defined herein. Also disclosed is a method for treating a cannabinoid receptor-mediated disorder with these compounds.

Process for Preparing Bicyclic Pyrazolyl

A process for preparing compounds of Formula (I) is described herein. The compounds have been shown to act as cannabinoid receptor ligands and are therefore useful in the treatment of disease linked to the mediation of the cannabinoid receptors in animals.

CANNABINOID RECEPTOR LIGANDS AND USES THEREOF

Compounds of Formula (I) that act as cannabinoid receptor ligands and their uses in the treatment of diseases linked to the mediation of the cannabinoid receptors in animals are described herein.

Cannabinoid receptor ligands and uses thereof

Compounds of Formula (I) that act as cannabinoid receptor ligands and their uses in the treatment of diseases linked to the mediation of the cannabinoid receptors in animals are described herein.