78429-79-5Relevant academic research and scientific papers
Chemoselectivity in the microwave-assisted solvent-free solid-liquid phase benzylation of phenols: O- versus C-alkylation
Keglevich, Gy?rgy,Bálint, Erika,Karsai, éva,Grün, Alajos,Bálint, Mária,Greiner, István
, p. 5039 - 5042 (2008/12/22)
The outcome of the solvent-free benzylation of phenol and 4-substituted phenols (such as 4-cresol and 4-chlorophenol) under MW irradiation was found to depend on the absence or presence of the base (K2CO3) and catalyst (triethylbenzy
Gas-phase Reactions of 2-Benzyl- and 2-Benzoyl-phenoxyl Radicals, and of 2-Phenoxybenzyl Radicals: Examples of New Hydrogen-transfer Processes
Cadogan, J. I. G.,Hutchison, H. Susan,McNab, Hamish
, p. 385 - 393 (2007/10/02)
Generation of the 2-benzylphenoxyl radical 23 or the 2-phenoxybenzyl radical 24 by flash vacuum pyrolysis of the ethers 8 or 9, or the oxalate 19, respectively, leads to fluoren-1-ol 22 together with 2-benzylphenol 7 and a low yield of xanthene 21.Pyrolysis of the para-substituted derivatives 11 and 20 gives an analogous distribution of products, including two isomeric methylxanthenes 28 and 29 formed via the spirodienyl 27.The reactions of the corresponding 2-benzoylphenoxyl radicals give information on the mechanism of these processes.Thus the formation of the fluorenones 37 and 43 provides evidence for the hydrogen-abstraction mechanism (Scheme 4) of fluorene formation.Secondly, a detailed study of the ratios of xanthones 41 and 42 under a variety of pyrolysis conditions suggests that such 6-membered-ring products are formed by sigmatropic shifts in the spirodienyl, rather than direct cyclisation of the phenoxyl or benzoyl radicals.
