78456-49-2

Upstream product

• 141-78-6 ethyl acetate 
• 583-60-8 2-Methylcyclohexanone 
• 19980-33-7 6-methyl-1-trimethylsiloxycyclohex-1-ene 
• 2261-02-1 acetylium tetrafluoroborate 
• 75-36-5 acetyl chloride 
• 7637-07-2 boron trifluoride 
• 108-24-7 acetic anhydride 
• 1193-63-1 Cyclohexanone-2-carbaldehyde 

Downstream Products

• 837363-81-2 (5E)-5-(3-methyl-2-oxocyclohexylidene)-1-phenyl-3-(phenylamino)-1H-pyrrol-2(5H)-one 
• 837363-84-5 (E)-3-(4-methoxyphenylamino)-1-(4-methoxyphenyl)-5-(6-methyl-2-oxocyclohex-1-ylidene)-2,5-dihydropyrrol-2-one 
• 837363-82-3 5-(3-methyl-2-oxo-cyclohexylidene)-1-o-tolyl-3-o-tolylamino-1,5-dihydro-pyrrol-2-one 
• 837363-83-4 (5E)-3-(2-methoxyphenylamino)-1-(2-methoxyphenyl)-5-(3-methyl-2-oxocyclohexylidene)-1H-pyrrol-2(5H)-one 

Relevant academic research and scientific papers

Synthesis of 5-alkylidene-2,5-dihydropyrrol-2-ones and their ring-transformation into 5,6-dihydrobenzo[h]chromones, 5,6,7,8-tetrahydrochromones and pyran-4-ones

Acid-mediated ring-transformations of 5-alkylidene-2,5-dihydropyrrol-2-ones, available by cyclization of 1,3-diketone dianions with bis(imidoyl) dichlorides of oxalic acid, resulted in formation of functionalized pyran-4-ones, such as 5,6-dihydrobenzo[h]c

Acylation of Ketone Silyl Enol Ethers with Acetyl Tetrafluoroborate. A Synthesis of 1,3-Diketones

Silyl enol ethers, obtained by silylation of ketones, are acylated with acetyl tetrafluoroborate to give 1,3-diketones in reasonable yields.Thetert-butyldimethylsilyl enol ether of cyclohexanone gives a nearly quantitative yield of acetylcyclohexanone, while the trimethylsilyl enol ethers of cyclohexanone and other ketones give moderate yields of the corresponding 1,3-diketones.The regiospecificity of the reaction was studied with the isomeric silyl enol ethers of 2-methylcyclohexanone.