78485-37-7 Usage
Description
Ethyl 2-chloro-6-benzothiazolecarboxylate, also known as Ethyl 2-chloro-6-(phenylthio)benzothiazole-7-carboxylate, is a chemical compound with the molecular formula C13H9ClNOS. It is a versatile building block in the synthesis of pharmaceuticals and agrochemicals, known for its potential as an anti-cancer agent, and also possesses anti-inflammatory and anti-fungal properties.
Uses
Used in Pharmaceutical Industry:
Ethyl 2-chloro-6-benzothiazolecarboxylate is used as a building block for the synthesis of various pharmaceuticals due to its versatile chemical properties and potential therapeutic applications.
Used in Agrochemical Industry:
Ethyl 2-chloro-6-benzothiazolecarboxylate is also utilized as a building block in the development of agrochemicals, contributing to its role in pest control and crop protection.
Used in Anti-cancer Applications:
Ethyl 2-chloro-6-benzothiazolecarboxylate is used as a potential anti-cancer agent for its ability to inhibit the growth of cancer cells, offering a promising avenue for cancer treatment research.
Used in Anti-inflammatory and Anti-fungal Applications:
Due to its anti-inflammatory and anti-fungal properties, Ethyl 2-chloro-6-benzothiazolecarboxylate is used in the development of treatments for inflammatory conditions and fungal infections.
It is important to handle Ethyl 2-chloro-6-benzothiazolecarboxylate with care, as it is classified as a hazardous substance and can cause irritation to the skin, eyes, and respiratory system.
Check Digit Verification of cas no
The CAS Registry Mumber 78485-37-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,4,8 and 5 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 78485-37:
(7*7)+(6*8)+(5*4)+(4*8)+(3*5)+(2*3)+(1*7)=177
177 % 10 = 7
So 78485-37-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H8ClNO2S/c1-2-14-9(13)6-3-4-7-8(5-6)15-10(11)12-7/h3-5H,2H2,1H3
78485-37-7Relevant articles and documents
Benzothiazole derivatives and medical application thereof
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Paragraph 0016-0018, (2021/07/17)
The invention discloses benzothiazole derivatives and a medical application thereof. The invention provides a series of benzothiazole derivatives, and research finds that the series of benzothiazole derivatives can effectively improve the expression level
NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AS FXR MODULATORS
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Paragraph 0112; 0113, (2018/05/24)
The present technology is directed to compounds, compositions, and methods related to modulation of FXR. In particular, the present compounds and compositions may be used to treat FXR-mediated disorders and conditions, including, e.g., liver disease, hype
FXR RECEPTOR MODULATOR, PREPARATION METHOD THEREFOR, AND USES THEREOF
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, (2018/11/27)
The present disclosure disclosed a modulator of FXR receptor and preparation and use thereof, which relates to the technical filed of medicinal chemistry. The present disclosure provides a modulator of FXR receptor having a structural formula I or a pharmaceutically acceptable salt, stereoisomer, solvate or prodrug thereof, which can combine with FXR receptor (that is NR1H4) and be acted as a FXR agonist or a partial agonist for preventing and treating the disease mediated by FXR, such as chronic intrahepatic or extrahepatic cholestasis, hepatic fibrosis caused by chronic cholestasis or acute intrahepatic cholestasis, chronic hepatitis B, gallstone, hepatic carcinoma, colon cancer or intestinal inflammatory disease, etc. Specifically, for some chemical compounds, their EC50 for FXR agonist activity reach below 100nM, which show an excellent FXR agonist activity and an excellent prospect to provide a new pharmaceutical selection in clinical treatment for the disease mediated by FXR.
