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ETHYL 4-AMINO-3-FLUOROBENZOATE is a chemical compound with the molecular formula C9H10NO2F. It is a derivative of benzoic acid, featuring a fluorine atom at the 3-position and an amino group at the 4-position. ETHYL 4-AMINO-3-FLUOROBENZOATE is widely utilized in organic synthesis and medicinal chemistry as a key building block for the development of pharmaceuticals and agrochemicals. Additionally, it has been investigated for its potential pharmacological properties, such as anti-inflammatory and analgesic effects. ETHYL 4-AMINO-3-FLUOROBENZOATE also finds application as a flavoring or fragrance agent in the perfume industry, and it is crucial to handle it with caution due to its potential hazards.

73792-12-8

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73792-12-8 Usage

Uses

Used in Organic Synthesis:
ETHYL 4-AMINO-3-FLUOROBENZOATE is used as a building block in organic synthesis for the preparation of various pharmaceuticals and agrochemicals. Its unique structure with a fluorine atom and an amino group allows for versatile chemical reactions, making it a valuable component in the synthesis of complex organic molecules.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, ETHYL 4-AMINO-3-FLUOROBENZOATE is employed as a key intermediate for the development of new drugs. Its presence in the molecular structure can influence the pharmacokinetic and pharmacodynamic properties of the resulting compounds, contributing to their therapeutic efficacy.
Used in Pharmaceutical Industry:
ETHYL 4-AMINO-3-FLUOROBENZOATE is used as an active pharmaceutical ingredient or as a precursor in the synthesis of various medications. Its potential pharmacological properties, such as anti-inflammatory and analgesic effects, make it a promising candidate for the development of new therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical industry, ETHYL 4-AMINO-3-FLUOROBENZOATE is utilized as a starting material for the synthesis of pesticides and other agrochemicals. Its unique chemical structure can contribute to the development of more effective and environmentally friendly products.
Used as a Flavoring or Fragrance Agent:
ETHYL 4-AMINO-3-FLUOROBENZOATE is used as a flavoring or fragrance agent in the production of perfumes and other scented products. Its distinct chemical properties can impart unique and desirable aromas to these products.
Safety Considerations:
Due to its potential hazards, it is important to handle ETHYL 4-AMINO-3-FLUOROBENZOATE with care. Proper safety measures, such as wearing protective equipment and following established protocols, should be implemented to minimize risks associated with its use.

Check Digit Verification of cas no

The CAS Registry Mumber 73792-12-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,7,9 and 2 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 73792-12:
(7*7)+(6*3)+(5*7)+(4*9)+(3*2)+(2*1)+(1*2)=148
148 % 10 = 8
So 73792-12-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H10FNO2/c1-2-13-9(12)6-3-4-8(11)7(10)5-6/h3-5H,2,11H2,1H3

73792-12-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name ETHYL 4-AMINO-3-FLUOROBENZOATE

1.2 Other means of identification

Product number -
Other names 4-amino-3-fluoro-benzoic acid ethyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:73792-12-8 SDS

73792-12-8Relevant academic research and scientific papers

ROR[gamma] inhibitors, preparation method thereof and application of the ROR[gamma] inhibitors in medicine

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Paragraph 0365-0369, (2021/05/26)

The present specification provides compounds of formula (I) shown in the specification: or a pharmaceutically acceptable salt thereof, a deuterated compound, a tautomer, a cis-trans-isomer, a mesomer, a raceme, an enantiomer, a diastereoisomer, or a mixtu

Synthesis of 2 - fluoro aniline compounds of the method

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Paragraph 0122; 0123; 0125; 0126; 0127, (2019/05/15)

The invention discloses a method for synthesizing 2 - fluoro aniline compounds of the method, the method is: shown in formula Ia aniline compound of formula Ib α and β shown aniline compound as raw materials, through coupling reaction shown [...] azobenzene compound II, then the type II shown azobenzene compound with a palladium catalyst, fluorination reagent, additive, organic solvent, in the 30 - 150 °C temperature closed agitating the fluorination reaction, [...] compound of formula III, type III compounds are shown in the reaction under the action of a reducing [...] shown IV 2 - fluoro aniline compounds; this invention synthetic 2 - fluoro aniline compounds substrate wide adaptability, mild reaction conditions, the operation is simple, fluorinated and good selectivity, [...] aniline compounds is prepared by many drug molecule is an important intermediate and starting material, wide application prospects.

Silver-catalyzed intermolecular amination of fluoroarenes

Wang, Yu,Wei, Chenlong,Tang, Ruyun,Zhan, Haosheng,Lin, Jing,Liu, Zhenhua,Tao, Weihua,Fang, Zhongxue

supporting information, p. 6191 - 6194 (2018/09/10)

A novel highly selective Ag-catalyzed intermolecular amination of fluoroarenes has been developed. This transformation starts from readily available 4-carbonyl fluorobenzene and NaN3 or other nitrogen-source, via amination followed by C-F bond cleavage, thus affording the desired 4-carbonyl arylamine products under mild conditions. The reaction is accelerated using a small amount of water. This pathway is distinct from a previously reported radical amination reaction.

NEW CYCLOHEXYLAMINE DERIVATIVES HAVING β2 ADRENERGIC AGONIST AND M3 MUSCARINIC ANTAGONIST ACTIVITIES

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Page/Page column 67-68, (2011/12/02)

The present invention relates to novel compounds having β2 adrenergic agonist and M3 muscarinic antagonist dual activity, to pharmaceutical compositions containing them, to the process for their preparation and to their use in respiratory therapies.

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