78494-26-5

Basic information

• Product Name: 3-(4-Fluorophenyl)cyclohexanone
• Synonyms: 3-(4-Fluorophenyl)cyclohexanone
• CAS NO: 78494-26-5
• Molecular Formula: C₁₂H₁₃FO
• Molecular Weight: 192.2294232
• Mol File: 78494-26-5.mol
• Article Data: 24

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(4-Fluorophenyl)cyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-Fluorophenyl)cyclohexanone(78494-26-5)
• EPA Substance Registry System: 3-(4-Fluorophenyl)cyclohexanone(78494-26-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 78494-26-5(Hazardous Substances Data)

Upstream product

• 930-68-7 cyclohexenone 
• 824-80-6 sodium 4-fluorobenzenesulfinate 
• 1146127-04-9 4-fluoro-2,4,6-trimethyldiphenyliodonium trifluoromethanesulfonate 
• 108-94-1 cyclohexanone 
• 1579298-06-8 1-(1-(4-fluorophenyl)-vinyl)cyclobutan-1-ol 
• 725735-33-1 triallyl(4-fluorophenyl)silane 
• 352-34-1 4-fluoro-1-iodobenzene 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 25776-12-9 sodium tetrakis(4-fluorophenyl)borate 
• 1765-93-1 4-fluoroboronic acid 
• 448-59-9 tris(4-fluorophenyl)boroxine 
• 352-13-6 4-flourophenylmagnesium bromide 

Downstream Products

• 1141891-74-8 C₁₄H₁₅FO₃ 
• 10540-41-7 4'-fluoro-[1,1'-biphenyl]-3-ol 

Relevant articles and documents

The synthesis method of one-carbon ring expansion of cycloketone dericatives from β-selenyl cycloketone dericatives

The present invention relates to a method for preparing a cyclic ketone derivative with an increased carbon number by performing a ring expansion reaction of a β-selenyl cyclic ketone derivative. The present invention was first developed by performing the

A consecutive process for C-C and C-N bond formation with high enantio-and diastereo-control: Direct reductive amination of chiral ketones using hydrogenation catalysts

High diastereoselectivity was observed in the Rh-catalysed reductive amination of 3-arylcyclohexanones to form tertiary amines. This was incorporated into a one-pot enantioselective conjugate addition and diastereoselective reductive amination, including an example of assisted tandem catalysis.

Rh-catalyzed 1,4-addition of triallyl(aryl)silanes to α,β-unsaturated carbonyl compounds

Rh-catalyzed 1,4-addition of triallyl(aryl)silane to α,β-unsaturated carbonyl compounds was developed. Triallyl(aryl)silanes were used as air- and moisture-stable silicon nucleophiles. Allylsilanes were converted to silanols in situ and underwent transmetalation. This method can accept a wide range of functionalized triallyl(aryl)silane and α,β-unsaturated carbonyl compounds.