785-93-3

Basic information

• Product Name: Benzenemethanol, a-(heptafluoropropyl)-
• CAS NO: 785-93-3
• Molecular Formula: C10H7F7O
• Molecular Weight: 276.154
• Mol File: 785-93-3.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, a-(heptafluoropropyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-(heptafluoropropyl)-(785-93-3)
• EPA Substance Registry System: Benzenemethanol, a-(heptafluoropropyl)-(785-93-3)

Safety Data

• Hazardous Substances Data: 785-93-3(Hazardous Substances Data)

Upstream product

• 356-24-1 methyl heptafluorobutyrate 
• 920-39-8 isopropylmagnesium bromide 
• 16002-63-4 phenylmagnesium iodide 
• 422-89-9 heptafluoro-propyl lithium 
• 100-52-7 benzaldehyde 
• 754-34-7 1,1,1,2,2,3,3-heptafluoro-3-iodo-propane 
• 3834-42-2 (heptafluoropropyl)trimethylsilane 
• 100-58-3 phenylmagnesium bromide 
• 2252-84-8 HFC-227ca 
• 93-58-3 benzoic acid methyl ester 
• 559-91-1 1-phenylperfluorobutan-1-one 

Downstream Products

• 884855-24-7 1-chloro-1-phenyl-2,2,3,3,4,4,4-heptafluorobutane 
• 944395-88-4 1,2,2,3,3,4,4,4-octafluoro-1-phenyl-butane 
• 845712-73-4 2-(2,2,3,3,4,4,4-heptafluoro-1-phenyl-butoxy)-benzo[1,3,2]dioxaphosphinin-4-one 
• 100664-13-9 Phosphoric acid 2,2,3,3,4,4,4-heptafluoro-1-phenyl-butyl ester bis-(2,2,2-trifluoro-ethyl) ester 

Relevant articles and documents

Tandem reductive perfluoroalkylation of esters with perfluoroalkyl titanate-type reagents

The generation of stable perfluoroalkyl titanate-type reagents and their new type of reaction, tandem reductive perfluoroalkylation of esters, are shown to give perfluoroalkylated sec-alcohols in up to quantitative yield. Copyright

Asymmetric Hydrogenation of Aryl Perfluoroalkyl Ketones Catalyzed by Rhodium(III) Monohydride Complexes Bearing Josiphos Ligands

The asymmetric hydrogenation of 2,2,2-trifluoroacetophenones and aryl perfluoroalkyl ketones was developed using a unique, well-defined chloride-bridged dinuclear rhodium(III) complex bearing Josiphos-type diphosphine ligands. These complexes were prepared from [RhCl(cod)]2, Josiphos ligands, and hydrochloric acid. As catalyst precursors, they allow for the efficient and enantioselective synthesis (up to 99 % ee) of chiral secondary alcohols with perfluoroalkyl groups. This system does not require an activating base for the hydrogenation of 2,2,2-trifluoroacetophenones. Additionally, the enantioselective C=O hydrogenations of 2-phenyl-3-(haloacetyl)-indoles, a class of privileged structures in medicinal chemistry, is reported for the first time.

Method for Producing Fluorine-Containing Substituted Compound and Fluorine-Containing Substituted Compound

A method for producing a fluorine-containing substituted compound, the method including: introducing an organofluorine compound and an organolithium compound into a microreactor provided with a flow path capable of mixing a plurality of liquids, to thereby obtain a reaction product; and introducing, into the microreactor, the reaction product and an electrophile exhibiting electrophilic effect on the reaction product, to thereby obtain a fluorine-containing substituted compound.