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Usage

Uses

Used in Pharmaceutical Industry:
7-METHYL-1,2,3-TRIAZOLO(1,5-A)PYRIDINE is used as a building block for the synthesis of pharmaceuticals due to its unique structure and potential biological activities. Its incorporation into drug molecules can enhance their therapeutic properties and target specific biological pathways.
Used in Agrochemical Industry:
In the agrochemical industry, 7-METHYL-1,2,3-TRIAZOLO(1,5-A)PYRIDINE is employed as a key component in the development of new agrochemicals. Its chemical properties allow for the creation of compounds with improved pesticidal or herbicidal activities, contributing to more effective crop protection.
Used in Organic Synthesis:
7-METHYL-1,2,3-TRIAZOLO(1,5-A)PYRIDINE is used as an intermediate in the production of various organic compounds. Its reactivity and structural features make it a valuable precursor for the synthesis of a wide range of organic molecules, including those with potential applications in materials science, dyes, and other specialty chemicals.
Used in Medicinal Chemistry Research:
7-METHYL-1,2,3-TRIAZOLO(1,5-A)PYRIDINE is utilized in medicinal chemistry research for its potential biological activities. Researchers are investigating its interactions with biological targets and exploring its use in the development of new therapeutic agents, particularly in the areas of drug discovery and design.

InChI:InChI=1/C7H7N3/c1-6-3-2-4-7-5-8-9-10(6)7/h2-5H,1H3

Upstream product

• 38112-50-4 [1-(6-Methyl-pyridin-2-yl)-meth-(Z)-ylidene]-hydrazine 
• 6627-60-7 2-aminomethyl-6-methylpyridine 
• 1122-72-1 6-methyl-2-pyridinecarboxaldehyde 
• 82315-67-1 C₁₄H₁₅N₃O₂S 

Downstream Products

• 152091-32-2 1-(3-iodophenyl)-2-<1,2,3>triazolo<1,5-a>pyridin-7-ylethanol 
• 82315-64-8 7-hydroxymethyl-1,2,3-triazolo<1,5-a>pyridine 
• 82315-68-2 1-(p-methoxyphenyl)-2-(triazolopyridin-7-yl)ethanol 
• 13287-64-4 acetic acid 6-methyl-pyridin-2-ylmethyl ester 
• 60398-59-6 ((6-methylpyridin-2-yl)methyl)diphenylphosphine oxide 
• 82315-70-6 2-(6-dibromomethylpyridin-2-yl)-1-(p-methoxyphenyl)ethanol 
• 82325-35-7 2-(6-formylpyridine-2-yl)-1-(p-methoxyphenyl)ethanol 
• 152091-40-2 methyl (E)-3-<2-<6-<3-(3-butoxyphenyl)-3-oxopropenyl>pyridin-2-yl>-1-<oxy>ethyl>benzoate 
• 152091-36-6 (E)-methyl <1-<oxy>-2-<6-(3-oxoundec-1-enyl)pyridin-2-yl>ethyl>benzoate 
• 152091-35-5 3-[1-(tert-Butyl-dimethyl-silanyloxy)-2-(6-formyl-pyridin-2-yl)-ethyl]-benzoic acid methyl ester 
• 152091-33-3 methyl 3-(1-hydroxy-2-<1,2,3>triazolo<1,5-a>pyridin-7-ylethyl)benzoate 

Relevant academic research and scientific papers

Method for synthesizing [1,2,3]triazole[1,5-a]pyridines compound through non-catalyst N-N coupling reaction

The invention relates to a method for synthesizing [1,2,3]triazole[1,5-a]pyridines compound through non-catalyst N-N coupling reaction. The invention discloses an efficient method for synthesizing a product at one step without using a catalyst under a mild condition from a 2-pyridylamine compound and nitroso tert-butyl ester as a mild nitrogen atom source. The method is free from the catalyst, thereaction step is reduced, the condition is extremely mild, the efficiency is high, and the later modification can be performed on the biological active molecular, thereby facilitating the industrialproduction of [1,2,3]triazole[1,5-a]pyridines compound.

Copper-catalyzed aerobic carboxygenation and N-arylation of [1,2,3]triazolo[1,5-a]pyridines towards pyridinium triazolinone ylides

Copper-catalyzed aerobic oxyarylation of [1,2,3]triazolo[1,5-a]pyridines is developed. Notably molecular oxygen was utilized as one of the reagents and the transformation resulted in the formation of novel pyridinium triazolinone ylides. A basic mechanism for the one-pot process is proposed and further functionalization of the ylidic products were also presented.

Ruthenium-NHC-Catalyzed asymmetric hydrogenation of indolizines: Access to indolizidine alkaloids

Crossing N-bridges! A ruthenium/N-heterocyclic carbene (NHC) complex serves as the catalyst for the high-yielding and completely regioselective and asymmetric hydrogenation of substituted indolizines and 1,2,3-triazolo-[1,5-a] pyridines. This method shoul

Synthesis of structural analogs of leukotriene B4 and their receptor binding activity

Structural analogs of leukotriene B4 (LTB4) were designed using a preferred conformation of LTB4 (1). Appending an aromatic ring scaffold between LTB4 carbons 7 and 11 led to quinoline analogs 3 and 15. A simila

Triazolopyridines. Part 2. Preparation of 7-Substituted Triazolopyridines by Directed Lithiation

The lithiation reactions of 1,2,3-triazolopyridine (1) to give the 7-lithio-derivative (4; R = Li), and of its 7-methyl derivative (16) to give the 7-lithiomethyl compound, are described.These lithium derivatives react with electrophiles, notably a