785825-41-4

Usage

Uses

Used in Organic Synthesis:
(R)-1-Boc-N-methylpyrrolidine-2-carboxamide is used as a building block in organic synthesis for its versatile chemical structure and reactivity, allowing for the creation of various complex molecules.
Used in Pharmaceutical Research:
(R)-1-Boc-N-methylpyrrolidine-2-carboxamide is used as a potential drug candidate in pharmaceutical research due to its unique chemical structure and potential therapeutic applications, targeting the treatment of various medical conditions.
Used in the Development of Novel Drug Delivery Systems:
(R)-1-Boc-N-methylpyrrolidine-2-carboxamide can be utilized in the development of innovative drug delivery systems to enhance the bioavailability, delivery, and therapeutic outcomes of associated pharmaceutical compounds.
Used in the Chemical Industry:
(R)-1-Boc-N-methylpyrrolidine-2-carboxamide may be employed in the chemical industry for the synthesis of specialty chemicals, materials, or intermediates that require its specific structural features.

Upstream product

• 593-51-1 methylamine hydrochloride 
• 37784-17-1 N-(tert-butoxycarbonyl)-D-proline 
• 74-89-5 methylamine 

Downstream Products

• 783325-25-7 (R)-2-methylaminomethyl-1-BOC-pyrrolidine 

Relevant academic research and scientific papers

Distal Stereocontrol Using Guanidinylated Peptides as Multifunctional Ligands: Desymmetrization of Diarylmethanes via Ullman Cross-Coupling

We report the development of a new class of guanidine-containing peptides as multifunctional ligands for transition-metal catalysis and its application in the remote desymmetrization of diarylmethanes via copper-catalyzed Ullman cross-coupling. Through design of these peptides, high levels of enantioinduction and good isolated yields were achieved in the long-range asymmetric cross-coupling (up to 93:7 er and 76% yield) between aryl bromides and malonates. Our mechanistic studies suggest that distal stereocontrol is achieved through a Cs-bridged interaction between the Lewis-basic C-terminal carboxylate of the peptides with the distal arene of the substrate.

Novel diamino derivatives of [1,2,4]triazolo[1,5-a][1,3,5]triazine as potent and selective adenosine A2a receptor antagonists

Piperazine derivatives of 2-furanyl[1,2,4]triazolo[1,5-a][1,3,5]triazine have recently been demonstrated to be potent and selective adenosine A 2a receptor antagonists with oral activity in rodent models of Parkinson's disease. We have replaced

TRIAZOLO[1,5-C]PYRIMIDINES and PYRAZOLO[1,5-C]PYRIMIDINES AND METHODS OF MAKING AND USING THE SAME

The invention is based on the discovery that compounds of formula (I) possess unexpectedly high affinity for the A2a adenosine receptor, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including Parkinson's disease. In one embodiment, the invention features a compound of formula (I) .

TRIAZOLO[1,5-A]PYRIMIDINES and PYRAZOLO[1,5-A]PYRIMIDINES AND METHODS OF MAKING AND USING THE SAME

The invention is based on the discovery that compounds of formula (I) possess unexpectedly high affinity for the A2a adenosine receptor, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including Parkinson's disease. In one embodiment, the invention features a compound of formula (I) .