78593-40-5Relevant articles and documents
Synthesis, characterization and palladium complex formation of pyridinium- and quinolinium-3-acetylides: Mesomeric betaines or betaine-stabilized carbenes?
Smeyanov, Alexey,Namyslo, Jan C.,Hübner, Eike,Nieger, Martin,Schmidt, Andreas
, p. 6665 - 6671 (2015)
3-Ethynyl-1-methylpyridinium- and 3-ethynyl-1-methyl-quinolinium triflates were prepared by methylation of 3-ethynylpyridine and 3-ethynylquinoline with methyl triflate, respectively. Whereas deprotonation of the former mentioned salt gave no stable produ
Aryl Nitriles from Alkynes Using tert -Butyl Nitrite: Metal-Free Approach to C≡C Bond Cleavage
Dutta, Uttam,Lupton, David W.,Maiti, Debabrata
, p. 860 - 863 (2016/03/01)
Alkyne C≡C bond breaking, outside of alkyne metathesis, remains an underdeveloped area in reaction discovery. Recently, nitrogenation has been reported to allow nitrile formation from alkynes. A new protocol for the metal-free C≡C bond cleavage of terminal alkynes to produce nitriles is reported. This method provides an opportunity to synthesize a vast range of nitriles containing aryl, heteroaryl, and natural product derivatives (38 examples). In addition, the potential of tBuONO to act as a powerful nitrogenating agent for terminal aryl alkynes is demonstrated. (Figure Presented).
Aerobic oxynitration of alkynes with tBuONO and TEMPO
Dutta, Uttam,Maity, Soham,Kancherla, Rajesh,Maiti, Debabrata
, p. 6302 - 6305 (2015/02/19)
An efficient method for stereoselective nitroaminoxylation of alkyne has been reported. The reaction enjoys a broad substrate scope, good functional group tolerance, and high yields. Synthetically useful α-nitroketones can be accessed through these products in a single step.