78597-27-0 Usage
Uses
Used in Pharmaceutical Industry:
5-IODO-1H-BENZIMIDAZOLE is used as a chemical intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
5-IODO-1H-BENZIMIDAZOLE is used as a precursor in the production of agrochemicals, aiding in the creation of compounds that can be used in agriculture for pest control and crop protection.
Used in Materials Science:
5-IODO-1H-BENZIMIDAZOLE is employed in the synthesis of materials for various industrial applications, including the development of new materials with specific properties for use in different sectors.
Used as a Research Chemical:
5-IODO-1H-BENZIMIDAZOLE is utilized as a research chemical, enabling scientists to study its properties and explore its potential applications in various fields.
Used in Organic Synthesis:
5-IODO-1H-BENZIMIDAZOLE is used as a reagent in organic synthesis, facilitating the creation of new organic compounds and contributing to advancements in chemical research.
Used in Anticancer Applications:
5-IODO-1H-BENZIMIDAZOLE is being investigated for its potential anticancer properties, with the aim of developing new treatments for various types of cancer.
Used in Antimicrobial Applications:
5-IODO-1H-BENZIMIDAZOLE is also being explored for its antimicrobial properties, with the potential to be used in the development of new antimicrobial agents to combat resistant bacteria and other pathogens.
Check Digit Verification of cas no
The CAS Registry Mumber 78597-27-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,5,9 and 7 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 78597-27:
(7*7)+(6*8)+(5*5)+(4*9)+(3*7)+(2*2)+(1*7)=190
190 % 10 = 0
So 78597-27-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H5IN2/c8-5-1-2-6-7(3-5)10-4-9-6/h1-4H,(H,9,10)
78597-27-0Relevant academic research and scientific papers
PROTEIN KINASE INHIBITORS
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Page/Page column 39, (2014/10/18)
A compound of formula (I), wherein R1 to R5, A, B, Z, Z1 and Z2 are as defined in the claims, and pharmaceutically acceptable salts thereof are disclosed. The compounds of formula (I) possess utility as FGFR inhibitors and are useful in the treatment of a condition, where FGFR kinase inhibition is desired, such as cancer.
Mild and general one-pot reduction and cyclization of aromatic and heteroaromatic 2-nitroamines to bicyclic 2 H -imidazoles
Hanan, Emily J.,Chan, Bryan K.,Estrada, Anthony A.,Shore, Daniel G.,Lyssikatos, Joseph P.
experimental part, p. 2759 - 2764 (2010/12/25)
A one-pot procedure for the conversion of aromatic and heteroaromatic 2-nitroamines into bicyclic 2H-benzimidazoles is described. The procedure employs formic acid, iron powder, and an additive such as NH4Cl to reduce the nitro group and effect the imidazole cyclization with high-yielding conversions generally within one to two hours. The compatibility with a wide range of functionality demonstrates the general utility of this procedure.
