78743-29-0Relevant academic research and scientific papers
Synthesis and antitumor activities of novel benzoylphenylurea derivatives
Okada,Koyanagi,Yamada,Haga
, p. 2308 - 2315 (1991)
Seventy novel benzoylphenylurea compounds were synthesized and their antitumor activities were examined in vivo against P388 leukemia. N-(2-Nitrobenzoyl)-N'-[4-(2-pyrimidinyloxy)phenyl]ureas showed the highest antitumor activities when dosed intraperitoneally or orally. Their structure-activity relationships were examined with particular focus on the position and the variety of substituent on each aryl ring.
N-benzoyl N'-pyridyloxy phenyl urea
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, (2008/06/13)
Compounds having the formula STR1 wherein X represents a halogen atom, nitro, methyl, or trifluoromethyl group; Y represents a halogen or hydrogen atom or methyl group; and Z represents a halogen atom are useful as agricultural chemicals and pharmaceutica
