78750-03-5Relevant articles and documents
Visible-light-initiated photo-oxidative cyclization of phenolic amidines using CBr4-A metal free approach to 2-aminobenzoxazoles
Keshari, Twinkle,Srivastava, Vishnu P.,Yadav, Lal Dhar S.
, p. 5815 - 5818 (2014/01/23)
A mild and efficient one-pot operation for the amination of benzoxazoles has been achieved via ring opening of benzoxazoles followed by visible-light-mediated aerobic photo-oxidative cyclization of the resulting o-phenolic amidines using CBr4 as a mild oxidant. The protocol is economical and environmentally benign as it utilizes visible light and does not require any photosensitizers, additives, heating or inert conditions.
Synthesis of 2-aminobenzoxazoles via copper-catalyzed electrophilic amination of benzoxazoles with O-benzoyl hydroxylamines
Yotphan, Sirilata,Beukeaw, Danupat,Reutrakul, Vichai
, p. 6627 - 6633 (2013/07/26)
An efficient copper-catalyzed electrophilic amination of benzoxazoles with O-benzoyl hydroxylamines is described, employing CuCl catalyst, PPh3 ligand, and LiOtBu base. This simple air-stable copper catalysis enables the preparation of various 2-aminobenzoxazole derivatives at room temperature in good yields.
Amination of benzoxazoles and 1,3,4-oxadiazoles using 2,2,6,6- tetramethylpiperidine-N-oxoammonium tetrafluoroborate as an organic oxidant
Wertz, Sebastian,Kodama, Shintaro,Studer, Armido
, p. 11511 - 11515 (2012/01/11)
No transition metals are necessary to convert benzoxazoles and 1,3,4-oxadiazoles into the corresponding pharmacologically interesting 2-aminated heterocycles by formal direct C(2)-amination using tetramethylpiperidine-N-oxoammonium tetrafluoroborate (TEMPO+BF 4-) as an oxidant (see scheme; TEMP=2,2,6,6- tetramethylpiperidine; TfOH=trifluoromethanesulfonic acid).