78755-14-3

Basic information

• Product Name: 4-pyrrolidino-1-(2H)-phthalazinone
• CAS NO: 78755-14-3
• Molecular Weight: 215.255
• Mol File: 78755-14-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-pyrrolidino-1-(2H)-phthalazinone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-pyrrolidino-1-(2H)-phthalazinone(78755-14-3)
• EPA Substance Registry System: 4-pyrrolidino-1-(2H)-phthalazinone(78755-14-3)

Safety Data

• Hazardous Substances Data: 78755-14-3(Hazardous Substances Data)

Upstream product

• 123-75-1 pyrrolidine 
• 2257-69-4 1-chloro-4-phthalazinone 

Downstream Products

• 1431735-53-3 2-{3-[4-(3-acetamidophenyl)piperidin-1-yl]propyl}-4-(pyrrolidin-1-yl)phthalazin-1(2H)-one 

Relevant articles and documents

AMINOPHTHALAZINONE DERIVATIVES, VII REACTION OF CHLOROPHTHALAZINONE WITH SECONDARY AMINES STUDY OF THE STERIC EFFECT, II

In the aminolysis of chlorophthalazinone (1a) with secondary amines, the yield of N-substitution (1 5, 1 7) is significantly affected by the steric structure of the amine.In the cyclic secondary amines substituents at the C-2 position give rise to a strong steric hindrance.The possibility for N-substitution gradually decreases with increasing size of the ring, while in the case of open-chain secondary amines it varies suddenly as a function of the position of the NH group in the chain.