787632-44-4

Upstream product

• 787632-43-3 N-[(1R,2S,3R)-3-Hydroxy-2-(4-methoxy-benzyloxy)-1-(4-methoxy-phenoxymethyl)-pent-4-enyl]-acetamide 
• 824-94-2 p-methoxybenzyl chloride 
• 544455-38-1 ethyl (2E)-4-(4-methoxyphenoxy)but-2-enoate 
• 544455-39-2 (2S,3R)-3-Acetylamino-2-hydroxy-4-(4-methoxy-phenoxy)-butyric acid ethyl ester 
• 787632-40-0 N-[(1R,2S)-2-(4-Methoxy-benzyloxy)-1-(4-methoxy-phenoxymethyl)-3-oxo-propyl]-acetamide 
• 787632-48-8 (2S,3R)-3-Acetylamino-2-(4-methoxy-benzyloxy)-4-(4-methoxy-phenoxy)-butyric acid ethyl ester 
• 787632-41-1 N-[(1R,2S,3S)-3-Hydroxy-2-(4-methoxy-benzyloxy)-1-(4-methoxy-phenoxymethyl)-pent-4-enyl]-acetamide 

Downstream Products

• 128387-05-3 triacetyl-D-threo-sphingosine 

Relevant academic research and scientific papers

Stereoselective synthesis of trans-olefins by the copper-mediated SN2′ reaction of vinyl oxazines with Grignard reagents. Asymmetric synthesis of d-threo-sphingosines

The SN2′ reaction of 6-vinyl-5,6-dihydro-4H-[1,3]oxazines with Grignard reagents in the presence of CuCN was studied, and high trans selectivity for the formation of double bond was observed with a variety of RMgX. The SN2′ reaction,

Oxazine formation by MsCl/Et3N as a convenient tool for the stereochemical interconversion of the hydroxyl group in N-acetyl 1,3-aminoalcohols. Asymmetric synthesis of N-acetyl L-xylo- and L-arabino-phytosphingosines

Use of MsCl/Et3N was proven to provide a convenient synthetic tool for the stereochemical intercoversion of the hydroxyl group in N-acetyl 1,3-aminoalcohols. Thus, under these conditions, the alcohols 4 and 6 smoothly converted to the oxazines