788-57-8Relevant academic research and scientific papers
METHOD OF PRODUCING FIVE-CARBON RING-CONTAINING COMPOUND AND FIVE-CARBON RING DERIVATIVE-CONTAINING POLYURETHANE, AND FIVE-CARBON RING DERIVATIVE-CONTAINING POLYURETHANE
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, (2019/02/24)
A method of producing a five-carbon ring derivative-containing polyurethane involves introducing a DCPD-derived 5-carbon cyclic compound into a polyurethane material and effectuating polymerization in the presence of a solvent of a low boiling point and l
(METH)ACRYLIC RESIN COMPOSITION, FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE
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Paragraph 0264; 0269, (2017/01/23)
There is provided a (meth)acrylic resin composition containing a (meth)acrylic resin, and a compound denoted by General Formula (1) described below, a film formed by using the (meth)acrylic resin composition, and a polarizing plate and a liquid crystal display device including the film: wherein R1 to R8 each independently represent a hydrogen atom, a halogen atom, a hydroxyl group, or a hydrocarbon group having 1 to 12 carbon atoms, X represents a divalent alicyclic group having 4 to 20 carbon atoms, the alicyclic group represented by X may have at least one substituent group selected from a halogen atom, an aliphatic hydrocarbon group having 1 to 12 carbon atoms, and an aromatic hydrocarbon group having 6 to 15 carbon atoms.
Comparative investigations on the effects of pendent trifluoromethyl group to the properties of the polyimides containing diphenyl-substituted cyclopentyl Cardo-structure
Wang, Xuemei,Liu, Feng,Lai, Jiancheng,Fu, Zhiqiang,You, Xiaozeng
, p. 27 - 37 (2014/06/24)
Two series of Cardo-type polyimides (PIs), fluorinated or nonfluorinated, were prepared from condensation of the fluorinated Cardo-type diamine 1,1-bis[4-(4-amino-2-trifluoromethylphenoxy)phenyl]cyclopentane (BATFPCP) or the analogous nonfluorinated Cardo-type diamine 1,1-bis[4-(4-aminophenoxy)phenyl] cyclopentane (BAPCP) with four aromatic dianhydrides PMDA, ODPA, BTDA and BPDA, respectively. Both fluorinated and nonfluorinated PIs with Cardo-structure in polymer backbone generally retained good thermal properties comparable to aromatic PIs, with glass transition temperature (Tg) of 227-270 °C and 234-340°C, 5% weight loss temperature in nitrogen (air) of 471-483°C (448-474°C) and 472-482°C (464-492°C), respectively. The fluorinated and nonfluorinated PIs with Cardo-structure in the polymer backbone showed tensile strengths of 90.1-101.7 MPa and 78.6-99.6 MPa, tensile modulus of 1.44-1.83 GPa and 1.25-1.50 GPa, respectively, also comparable to those of the traditional aromatic PIs. In comparison with nonfluorinated series, the fluorinated PIs possessed better solubility, higher optical transparency and lower water absorption. The fluorinated PIs were readily soluble in a variety of organic solvents, exhibited high optical transparency and light color with the cut off wavelength at 373-424 nm and transmittance at 500 nm generally higher than 80%, and the water absorptions were measured as low as 0.18-0.93%. Additionally, the fluorinated series showed higher hydrophobicity by water contact angles and water absorption measurements and lower dielectric constant by dynamic dielectric measurements.
Structure-activity relationships of bisphenol a analogs at estrogen receptors (ERs): Discovery of an ERα-selective antagonist
Maruyama, Keisuke,Nakamura, Masaharu,Tomoshige, Shusuke,Sugita, Kazuyuki,Makishima, Makoto,Hashimoto, Yuichi,Ishikawa, Minoru
, p. 4031 - 4036 (2013/07/19)
Our multi-template approach for drug discovery, focusing on protein targets with similar fold structures, has yielded lead compounds for various targets. We have also shown that a diphenylmethane skeleton can serve as a surrogate for a steroid skeleton. H
An improved, highly efficient method for the synthesis of bisphenols
Patil,Suryawanshi,Pawar,Shinde
experimental part, p. 2016 - 2019 (2012/06/04)
An efficient synthesis of bisphenols is described by condensation of substituted phenols with corresponding cyclic ketones in presence of cetyltrimethylammonium chloride and 3-mercaptopropionic acid as a catalyst in extremely high purity and yields. Copyright E-Journal of Chemistry 2004-2011.
Structural optimization and biological evaluation of substituted bisphenol a derivatives as β-amyloid peptide aggregation inhibitors
Zhou, Yu,Jiang, Chunyi,Zhang, Yaping,Liang, Zhongjie,Liu, Wenfeng,Wang, Liefeng,Luo, Cheng,Zhong, Tingting,Sun, Yi,Zhao, Linxiang,Xie, Xin,Jiang, Hualiang,Zhou, Naiming,Liu, Dongxiang,Liu, Hong
experimental part, p. 5449 - 5466 (2010/11/05)
The aggregation of A? is a crucial step in the etiology of Alzheimer's disease. Our previous work showed that A? undergoes ?-helix/?-sheet intermediate structures during the conformational transition, and an A? aggregation inhibitor (1) was discovered by targeting the intermediates. Here, structure optimization toward compound 1 was performed and 34 novel derivatives were designed and synthesized. Nine compounds showed more effective inhibitory activity than the hit compound 1 in ThT fluorescence assay. Among them, compound 43 demonstrated more excellent inhibitory potency, which not only can suppress the aggregation of A? but also can dissolve the preformed fibrils as shown by CD spectroscopy, PICUP and AFM assays. Cellular assay indicated that 43 has no toxicity to neuronal cells, moreover, can effectively inhibit A? 1?42-induced neutrotoxicity and increase the cell viability. Together, on the basis of these positive results, these novel chemical structures may provide a promising potential for therapeutic applications in AD and other types of neurodegenerative disorders.
NOVEL DIAZONAPHTHOQUINONESULFONIC ACID BISPHENOL DERIVATIVE USEFUL IN PHOTO LITHOGRAPHIC SUB MICRON PATTERNING AND A PROCESS FOR PREPARATION THEREOF
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, (2010/04/25)
The present invention provides novel diazonaphthoquinonesulfonic acid bisphenol derivatives. More particularly, the present invention relates to photo restive coating comprising alkali-soluble resin, a photoactive compound and a surfactant. The photoresist film prepared has less then one micron. The photoactive compound is soluble or swellable in aqueous alkaline solutions and is diazonaphthoquinonesulfonic bisphenol esters of the general formula (A), wherein DNQ represents a 2-Diazo-1-naphthoquinone-4-sulfonyl, 2-Diazo-1-naphthoquinone-5-sulfonyl, 1-Diazo-2-naphthoquinone-4-sulfonyl groups and R1 R1 represents an alkyl, aryl and substituted aryl groups. The invention also provides a process for coating and imaging the light-sensitive composition.
NOVEL DIAZONAPHTHOQUINONESULFONIC ACID BISPHENOL DERIVATIVE USEFUL IN PHOTO LITHOGRAPHIC SUB MICRON PATTERNING AND A PROCESS FOR PREPARATION THEREOF
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Page/Page column 18, (2008/12/04)
The present invention provides novel diazonaphthoquinonesulfonic acid bisphenol derivatives. More particularly, the present invention relates to photo restive coating comprising alkali-soluble resin, a photoactive compound and a surfactant. The photoresist film prepared has less then one micron.The photoactive compound is soluble or swellable in aqueous alkaline solutions and is diazonaphthoquinonesulfonic bisphenol esters of the general formula (A), wherein DNQ represents a 2-Diazo-1-naphthoquinone-4-sulfonyl, 2-Diazo-1- naphthoquinone-5-sulfonyl, 1-Diazo-2-naphthoquinone-4-sulfonyl groups and R1 R1 represents an alkyl, aryl and substituted aryl groups. The invention also provides a process for coating and imaging the light-sensitive composition.
3,3-Diphenylpentane skeleton as a steroid skeleton substitute: Novel inhibitors of human 5α-reductase 1
Hosoda, Shinnosuke,Hashimoto, Yuichi
, p. 5414 - 5418 (2008/02/13)
We designed and synthesized novel type 1 5α-reductase inhibitors by using 3,3-diphenylpentane skeleton as a substitute for the usual steroid skeleton. 4-(3-(4-(N-Methylacetamido)phenyl)pentan-3-yl)phenyl dibenzylcarbamate (11k) is a competitive 5α-reductase inhibitor with the IC50 value of 0.84 μM.
