78807-77-9Relevant articles and documents
Synthesis and Biological Activity of Some New 10-phenothiazines
Jaiswal, Neelam,Jaiswal, R. K.,Barthwal, J. P.,Kishor, K.
, p. 252 - 253 (2007/10/02)
Fourteen 10-phenothiazines (IV) have been synthesized via condensation of 10-hydrazino-acetylphenothiazine with substituted benzalacetophenones.These compounds inhibit 33-86percent in vitro activity of rat brain pyruvate oxidase and afford protection against pentylenetetrazol induced seizures in albino mice.However, their anticonvulsant properties are found to be independent of their pyruvate oxidase inhibitory activity.