78843-65-9Relevant articles and documents
Catalytic asymmetric synthesis of diazabicyclo[3.1.0]hexanes by 1,3-dipolar cycloaddition of azomethine ylides with azirines
Adrio, Javier,Carretero, Juan C.,Díaz-Tendero, Sergio,Molina, Alba
supporting information, p. 5050 - 5053 (2020/05/18)
Substituted 1,3-diazabicyclo[3.1.0]hexanes with two contiguous quaternary stereocentres are readily prepared by catalytic asymmetric [3+2] cycloaddition of a-substituted iminoesters with azirines. High diastereoselectivities and enantioselectivities (up to 98% ee) are achieved using CuI/(R)-Fesulphos as the catalytic system.