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Usage

Uses

Used in Pharmaceutical Applications:
(2E,4E,8Z,10E,12E)-N-(2-methylpropyl)tetradeca-2,4,8,10,12-pentaenamide is used as a pharmaceutical agent for its potential therapeutic properties. (2E,4E,8Z,10E,12E)-N-(2-methylpropyl)tetradeca-2,4,8,10,12-pentaenamide's unique structure and unsaturation may contribute to its bioactivity, making it a candidate for the development of new drugs or drug delivery systems.
Used in Materials Science:
In the field of materials science, (2E,4E,8Z,10E,12E)-N-(2-methylpropyl)tetradeca-2,4,8,10,12-pentaenamide is used as a component in the development of novel materials. Its long-chain and polyunsaturated nature may provide specific properties that can be harnessed for the creation of advanced materials with tailored characteristics.
Used in Chemical Research:
(2E,4E,8Z,10E,12E)-N-(2-methylpropyl)tetradeca-2,4,8,10,12-pentaenamide serves as a subject of chemical research for understanding its reactivity, stability, and potential interactions with other molecules. Studying (2E,4E,8Z,10E,12E)-N-(2-methylpropyl)tetradeca-2,4,8,10,12-pentaenamide can lead to insights into the behavior of similar long-chain, polyunsaturated amides and contribute to the advancement of organic chemistry.

Upstream product

• 142-83-6 trans,trans-2,4-Hexadienal 
• 98095-53-5 (2E,4E)-8-(Triphenyl-λ⁵-phosphanylidene)-octa-2,4-dienoic acid isobutyl-amide 
• 78-81-9 isobutylamine 
• 17102-64-6 Sorbyl alcohol 
• 148999-69-3 (6-methoxy-6-oxohexyl)triphenylphosphonium bromide 
• 4224-70-8 6-bromohexanoic acid 
• 14273-90-6 methyl 6-bromohexanoate 

Downstream Products

• 544-63-8 n-tetradecanoic acid 

Relevant academic research and scientific papers

Synthesis of γ-Sanshool and hydroxy-γ-Sanshool

Members of the family of polyunsaturated amide compounds known as the sanshools are found in various Zanthoxylum species such as Sichuan (or Szechuan) peppercorns (huajiao). γ-Sanshool and hydroxy-γ-sanshool have been synthesized from simple building bloc

Synthesis of Tetradecapentaenoic Acid Derivatives

A 12-stage method for the stereoselective synthesis of tetradecapentaenoic acid derivatives using phosphoric reagents was developed. The key step in the synthesis is the Z-selective Wittig reaction between sorbaldehyde and triphenylphosphonium (6-methoxycarbonyl)hexanilide, as well as the Ramirez-Corey-Fuchs reaction and the Trost-Kazmaier rearrangement. The synthesized (2E,4E,8Z,10E,12E)-N-isobutyltetradeca-2,4,8,10,12-pentaenamide corresponds to a natural compound called γ-Sansho?l.

METHOD FOR PRODUCING SANSHOOL

Provided are a method for producing a sanshool, which can produce a sanshool in a short process and with high stereoselectivity, as well as a novel diene iron complex compound that is a stable intermediate useful for the production method. The diene iron complex compound is represented by the following general formula (I): (in which A represents CO, P(RA)3, CN, NO, SO(RA)3, or N(RA)2; RA represents a straight chain or branched chain alkyl group having 1 to 4 carbon atoms or an aryl group having 6 to 12 carbon atoms; and one of R1 and R2 represents a hydrogen atom and the other one thereof represents a structure represented by the following formula (II)): (in which R represents a hydrogen atom, a hydroxyl group, or a methyl group).

Application of iron carbonyl complexation to the selective total synthesis of sanshools

We focused on the iron-complexes of sanshools (hydroxyl-α-sanshool, hydroxyl-β-sanshool, and γ-sanshool) as the key intermediates for the selective synthesis of these structurally unstable compounds. Consequently, we developed a concise and selective method for the total synthesis of sanshools in 5-6 steps (26-45% overall yield), including complexation of dienes with iron tricarbonyl group.

SYNTHESIS OF NATURAL POLYENE ISOBUTYLAMIDES. STEREOCHEMISTRY OF THE WITTIG REACTIONS

Unsaturated isobutylamide synthons are employed to make seven natural amides.The (Z)-selectivity of the Wittig reaction towards the newly formed olefinic bond in the seven examples is estimated by 13Cmr.