789462-13-1

Basic information

• Product Name: N-<4-(1,1-Dimethylethyl)phenylmethyl>-α-methyl-1-naphthalinmethanamin
• CAS NO: 789462-13-1
• Molecular Weight: 317.474
• Mol File: 789462-13-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-<4-(1,1-Dimethylethyl)phenylmethyl>-α-methyl-1-naphthalinmethanamin(CAS DataBase Reference)
• NIST Chemistry Reference: N-<4-(1,1-Dimethylethyl)phenylmethyl>-α-methyl-1-naphthalinmethanamin(789462-13-1)
• EPA Substance Registry System: N-<4-(1,1-Dimethylethyl)phenylmethyl>-α-methyl-1-naphthalinmethanamin(789462-13-1)

Safety Data

• Hazardous Substances Data: 789462-13-1(Hazardous Substances Data)

Upstream product

• 149879-57-2 N-<4-(1,1-Dimethylethyl)phenylmethyl>-phthalimid 
• 18880-00-7 1-(bromomethyl)-4-(1,1-dimethylethyl)benzene 

Relevant articles and documents

Synthesis of potential inhibitors of squalenepoxidase with conformationanl fixation of the structural elements of Butenafine

The synthesis of the naphthalinemethanamines 6b-h is reported. To obtain products with conformative rigidity, substituents with gradually increased space demand were placed into the α-position. Since the direct reductive amination of the naphthylalkanones 3 with the amines 9 or 10 was only of very limited use the α-substituted naphthalinmethanamines 2 and 4 were synthesized as useful intermediates by various methods and the desired N-substitution pattern of the target compounds was subsequently built up applying - mostly reductive - alkylation methods.