79044-04-5

Upstream product

• 74-85-1 ethene 
• 539-03-7 N-(4-chlorophenyl)acetamide 
• 57045-85-9 2-bromo-4-chloroacetanilide 
• 7486-35-3 tri-n-butyl(vinyl)tin 
• 116035-66-6 N-(4-chloro-2-iodophenyl)acetamide 

Downstream Products

• 864749-97-3 N-(4-chloro-2-vinyl-phenyl)-N-(2,5-dibromo-benzyl)-acetamide 
• 1810-72-6 2,6-dichloroquinoline 
• 947689-06-7 C₂₇H₂₇ClNO₆P 

Relevant academic research and scientific papers

A new method for the generation of indole-2,3-quinodimethanes and 2-(N-alkoxycarbonylamino)-1,3-dienes. Intramolecular Heck/Diels-Alder cycloaddition cascade starting from acyclic α-phosphono enecarbamates

An intramolecular Heck/Diels-Alder cycloaddition cascade starting from acyclic α-phosphono enecarbamates has been developed to prepare nitrogen heterocycles via indole-2,3-quinodimethanes and 2-(N-alkoxycarbonylamino)-1,3- dienes. The Royal Society of Che

Fused tricyclic compounds as inhibitors of 17beta-hydroxysteroid dehydrogenase 3

Fused tricyclic compounds, methods of using such compounds in the treatment of hormone sensitive diseases such as prostate cancer, and pharmaceutical compositions containing such compounds.

Fused heterotricyclic compounds as inhibitors of 17beta-hydroxysteroid dehydrogenase 3

Fused heterotricyclic compounds, methods of using such compounds in the treatment of hormone sensitive diseases such as prostate cancer, and pharmaceutical compositions containing such compounds.

Novel synthesis of 2-chloroquinolines from 2-vinylanilines in nitrile solvent

2-Vinyl- or heteroaryl-substituted anilines were reacted with diphosgene in acetonitrile solution via a reactive imidoyl moiety to afford the corresponding 2-chloroquinolines. Facile syntheses of nine 2-chloroquinoline derivatives from several anilines and their postulate mechanism is described. The postulate mechanism of 2-chloroquinoline formation via imidoyl moiety as a good leaving group shows that the reaction consists of the following three steps: (1) generation of phenylisocyanate, (2) quinoline ring formation, and (3) chlorination on C2 position of quinoline.

Ortho Vinylation of Aromatic Amides via Cyclopalladation Complexes

The reaction of acetanilide and meta- and para-substituted acetanilides with palladium acetate has given new ortho-palladated complexes 2a-j, which reacted with carbon monoxide, ethylene, or methyl vinyl ketone to produce the corresponding N-acylanthranilic esters 4a-m, 2-acetaminostyrenes 9k-p, and 4-aryl-3-buten-2-one derivatives 9a-j, respectively.Reactions of 2a with substituted olefins proceeded readily to give the 2-olefins 8a-h.Ortho-substituted acetanilides and N-methylacetanilide did not undergo complex formation with palladium acetate.