116035-66-6Relevant articles and documents
Synthesis of 2,4-dihalogenofluorobenzenes and their antimicrobial and antifungal activity studies
Katircioglu, Hikmet,Logoglu, Elif,Tilki, Tahir,Oektemer, Atilla
, p. 205 - 212 (2007)
The aim of this study was to synthesize and identify 2,4- dihalogenofluorobenzene (or trihalogenobenzene) derivatives by spectroscopic means, 1H-NMR and 19F-NMR. The 2,4-dihalofluorobenzene derivatives considered were 2,4-dichlorofluorobenzene (1), 2-bromo-4- chlorofluorobenzene (2), 2-iodo-4-chlorofluorobenzene(3), 2,5- dichlorofluorobenzene (4), 2-bromo-5-chlorofluorobenzene (5), 2-iodo-5-chlorofluorobenzene (6). The in vitro antibacterial and antifungal activities of trihalogenobenzene derivatives were studied against the bacteria Staphylococcus aureus ATCC 25923 Gram(+), Bacillus cereus ATCC 6633 Gram(+), Micrococcus flavus (clinical isolate) Gram(+), Morgenella morganii (clinical isolate) Gram(-), Escherichia coli ATCC 27853 Gram(-) and fungus Candida albicans (clinical isolate), obtained from the biology departments of the Pamukkale and Gazi Universities. The antibacterial and antifungal activities were measured by minimum inhibition concentration (MIC) method and the disc-diffusion method used to measure zone diameter against Gram-positive and Gram-negative bacteria and fungi. All these bacteria and fungi were studied against antibiotics to compare the zone diameters with the results from our treatments. Birkhaeuser 2007.
Cobalt(II)-catalyzed regioselective C-H halogenation of anilides
Li, Ze-lin,Sun, Kang-kang,Cai, Chun
supporting information, p. 5433 - 5440 (2018/08/12)
A cobalt-catalyzed regioselective C-H halogenation methodology is reported herein. The highlight of this work is the highly selective C-H functionalization of anilides, which results in high-yielding, versatile, and practical halogenated products. Thereby, brominations, chlorinations and iodinations of many electron-rich and electron-deficient anilides were achieved in a highly selective fashion. Mechanistic studies with respect to the pathway of the reaction are also described.
Synthesis of 2,3-Disubstituted Indoles and Benzofurans by the Tandem Reaction of Rhodium(II)-Catalyzed Intramolecular C-H Insertion and Oxygen-Mediated Oxidation
Shen, Hongjuan,Fu, Junkai,Yuan, Hao,Gong, Jianxian,Yang, Zhen
, p. 10180 - 10192 (2016/11/17)
A highly effective and straightforward method to construct a wide range of functionalized 2,3-disubstituted indoles has been developed. The method involves the tandem reaction of rhodium(II)-catalyzed denitrogenative annulation of triazole-based benzyl an