79054-71-0

Basic information

• Product Name: N-tert-butyl-o-(methylthio)benzamide
• Synonyms: N-tert-butyl-o-(methylthio)benzamide
• CAS NO: 79054-71-0
• Molecular Weight: 223.339
• Mol File: 79054-71-0.mol

Chemical Properties

• CAS DataBase Reference: N-tert-butyl-o-(methylthio)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-tert-butyl-o-(methylthio)benzamide(79054-71-0)
• EPA Substance Registry System: N-tert-butyl-o-(methylthio)benzamide(79054-71-0)

Safety Data

• Hazardous Substances Data: 79054-71-0(Hazardous Substances Data)

Upstream product

• 1442-03-1 2-methylsulfanyl-benzoyl chloride 
• 75-64-9 tert-butylamine 
• 79894-32-9 N-t-butyl-2-(benzoyloxymethylthio)benzamide 
• 79894-26-1 N-Benzoyloxy-N-tert-butyl-2-methylsulfanyl-benzamide 
• 540-88-5 acetic acid tert-butyl ester 
• 6609-54-7 2-cyanothioanisole 
• 3724-10-5 2-(methylthio)benzoic acid 

Downstream Products

• 79054-65-2 N-t-butyl-2-(methylsulphinyl)benzamide 
• 79894-32-9 N-t-butyl-2-(benzoyloxymethylthio)benzamide 
• 79894-36-3 Acetic acid 2-tert-butylcarbamoyl-phenylsulfanylmethyl ester 

Relevant articles and documents

An efficient method for the conversion of aromatic and aliphatic nitriles to the corresponding N-tert-butyl amides: A modified Ritter reaction

Aromatic and aliphatic nitriles react with tert-butyl acetate in the presence of a catalytic amount of sulfuric acid to give the corresponding N-tert-butyl amides in excellent yields.

Synthetic method 1-2 - benzisothiazol -3 -one compound (by machine translation)

The invention discloses a synthetic method of 1-2 - benzisothiazol -3 -one compound, and belongs to the field of chemical synthesis. 2 - 1-benzisothiazol 2 -one compounds are synthesized through acid chlorination, amidation and cyclization reaction by using the sulfenyl-substituted benzoic acid extracted from BIT process -3 - waste water as a starting raw material. The method disclosed by the invention has the advantages of mild reaction conditions, simple and convenient operation, strong practicability, less waste water, high product purity and the like, and is suitable for large-scale industrial production. The technical scheme provided by the invention is resource utilization and preparation 1 of wastewater extract produced in BIT production, and a feasible method is provided for the 2 -benzisothiazol -3 -one compound. (by machine translation)

Benzisothiazol-3-ones through a Metal-Free Intramolecular N–S Bond Formation

The highly efficient synthesis of benzoisothiazol-3-ones from thiobenzamides has been described with good functional group compatibility and excellent yields. This work represents the first example of selectfluor-promoted N–S bond formation processes. This method provides a facile approach to access various important bioactive benzoisothiazol-3-ones.

Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones

A method for producing an alkylthiobenzamide by carrying out a reaction of a halobenzamide with an alkanethiol in the presence of a base in a heterogeneous solvent; a method for producing an alkylsulfinylbenzamide by carrying out a reaction of an alkylthi

The Thermal Decomposition of N,O-Diacyl-N-t-butylhydroxylamines. II. Thermal Rearrangement of O-Acyl-N--N-t-butylhydroxylamines

Several O-acyl-N--N-t-butylhydroxylamines (1) were prepared and their thermal decompositions were studied.The thermal decomposition of 1 at 200 deg C in o-dichlorobenzene gave N-t-butyl-2-(acyloxymethylthio)benzamide (4), the carboxylic acid derived from the acyl part of 1, and 2-t-butyl-1,2-benzothiazol-3(2H)-one as the main products, together with small amounts of 4H-3,1-benzoxathiin-4-one, N-t-butyl-2-(methylthio)benzamide, methyl ester of the carboxylic acid, and N-t-butylamide.The benzamide (4) was found to be an initial product of the thermolysis and the subsequent decomposition gave the carboxylic acid and other products.Pummerer type reaction, via acylaminosulfonium ion as the intermediate, was suggested for the thermal decomposition of 1 since similar products were also obtained by the Pummerer reaction of N-t-butyl-2-(methylsulfinyl)benzamide with acylating reagents.

A Novel Route to 2-Substituted 1,2-Benzisothiazol-3(2H)-ones

2-Alkyl- and 2-aryl-1,2-benzisothiazol-3(2H)-ones were synthesized in high yields by the cyclization of 2-(methylsulphinyl)benzamides with thionyl chloride.