79065-28-4

Basic information

• Product Name: 3H-2-methylimino-3-phenyl-5,7-dimethylpyrilo-<3,4-e>-1,3-thiazin-4-one
• CAS NO: 79065-28-4
• Molecular Weight: 297.381
• Mol File: 79065-28-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3H-2-methylimino-3-phenyl-5,7-dimethylpyrilo-<3,4-e>-1,3-thiazin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3H-2-methylimino-3-phenyl-5,7-dimethylpyrilo-<3,4-e>-1,3-thiazin-4-one(79065-28-4)
• EPA Substance Registry System: 3H-2-methylimino-3-phenyl-5,7-dimethylpyrilo-<3,4-e>-1,3-thiazin-4-one(79065-28-4)

Safety Data

• Hazardous Substances Data: 79065-28-4(Hazardous Substances Data)

Upstream product

• 70271-80-6 ethyl 4-chloro-2,6-dimethylnicotinate 
• 2724-69-8 1-methyl-3-phenylthiourea 

Relevant articles and documents

SYNTHESES AND PROPERTIES OF 3H-2-IMINO-5,7-DIMETHYLPYRIDO--1,3-THIAZIN-4-ONE DERIVATIVES

A number of new derivatives of 3H-2-imino-5,7-dimethylpyrido--1,3-thiazin-4-one (2) have been synthesized.The compounds were obtained in the reaction of 4-chloro-2,6-dimethylnicotinic acid ester (1) with differently N-substituted thioureas.Chloroester 1 with N-monoalkylthioureas in ethanol, forms a mixture of isomeric 2-alkyl and 3-alkyl derivatives and solely 2-alkyl isomers in acetic acid.It was demonstrated that in alkaline medium compound 2 reacted with methyl chlorocarbonate resulting in 3-methoxycarbonyl derivative, and with an excess of reagent it was transformed into 4-carbomethoxymercapto-2,6-dimethylnicotinoyl carbomethoxycyanamide (6).A mechanism of the reaction has been proposed.Pharmacologic analysis of the derivatives showed that some had antiinflammatory activity.