70271-80-6

Usage

Chemical Properties

Colorless liquid

InChI:InChI=1/C10H12ClNO2/c1-4-14-10(13)9-7(3)12-6(2)5-8(9)11/h5H,4H2,1-3H3

Upstream product

• 626-34-6 ethyl 3-aminobut-2-enoate 
• 141-97-9 ethyl acetoacetate 
• 33831-56-0 ethyl 4-hydroxy-2,6-dimethylpyridin-3-carboxylate 
• 10025-87-3 trichlorophosphate 
• 10026-13-8 phosphorus pentachloride 
• 626-34-6 ethyl aminocrotonate 

Downstream Products

• 86775-90-8 (2,6-dimethyl-pyridin-4-yl)-phenyl-amine 
• 846021-39-4 4-anilino-2,6-dimethyl-nicotinic acid 
• 89068-64-4 N⁴,N⁴-diethyl-N¹-(2,6-dimethyl-[4]pyridyl)-1-methyl-butanediyldiamine 
• 1721-13-7 ethyl 2,6-dimethylnicotinate 
• 33259-21-1 2,6-dimethyl-4-hydroxypyridine-3-carboxylic acid 
• 56022-09-4 2,6-dimethyl-4-chloronicotinoic acid 
• 13603-44-6 2,6-dimethylpyridin-4-ol 
• 79065-26-2 3H-2-imino-3-(p-sulfamylphenyl)-5,7-dimethylpyrido-<3,4-e>-1,3-thiazin-4-one 
• 79065-28-4 3H-2-methylimino-3-phenyl-5,7-dimethylpyrilo-<3,4-e>-1,3-thiazin-4-one 
• 79065-25-1 3H-2-imino-3-(p-chlorophenyl)-5,7-dimethylpyrido-<3,4-e>-1,3-thiazin-4-one 
• 87389-97-7 2,6,2',6'-Tetramethyl-[4,4']bipyridinyl-3,3'-dicarboxylic acid diethyl ester 
• 89155-13-5 2-Amino-3-(2-chloro-phenyl)-7,9-dimethyl-pyrano[2',3':4,5]thieno[3,2-c]pyridin-4-one 

Relevant academic research and scientific papers

AROMATIC RING COMPOUND

The present invention provides a compound having a GOAT inhibitory action, which is useful for the prophylaxis or treatment of obesity and the like, and has superior efficacy. The present invention is a compound represented by the formula (I): wherein eac

NICOTINIC ACID CROWN ETHERS: SYNTHESIS, COMPLEXATION AND REDUCTION

2,6-Bis(bromomethyl)nicotinic oxazoline (15), prepared from ethyl 2,6-dimethylnicotinate, was converted into the 1:1-macrocyclic oxazolines 19 and 22 as well as the isomeric macrocyclic dimers 20.Ethyl 2,6-bis(bromomethyl)nicotinate (23), prepared from 6b, was converted to the corresponding 1:1-dibenzo-18-crown-6 macrocyclic analog 24.NMR and mass spectral data were used to ascertain the macrocyclic structures.Reaction of 22 with EtMgBr afforded, after oxidation, the 4-substituted pyridino macrocycle 26 in high yield.However, under identical conditions, the non-oxazoline macrocycle 27 was recovered in toto.