790661-74-4Relevant academic research and scientific papers
Carbonylative Suzuki-Miyaura coupling reaction of lactam-, lactone-, and thiolactone-derived enol triflates for the synthesis of unsymmetrical dienones
Bartali, Laura,Guarna, Antonio,Larini, Paolo,Occhiato, Ernesto G.
, p. 2152 - 2163 (2008/02/06)
A thorough study of the carbonylative Suzuki-Miyaura cross-coupling reaction of enol triflates with alkenylboronic acids for the synthesis of unsymmetrical dienones is reported. Conditions were found that enabled the coupling of structurally different eno
Remote stereocontrol in the Nazarov reaction: A new approach to the core of roseophilin
Occhiato, Ernesto G.,Prandi, Cristina,Ferrali, Alessandro,Guarna, Antonio
, p. 4542 - 4545 (2007/10/03)
Three different procedures are compared to obtain properly substituted divinyl ketones in which one of the double bonds is embedded in a five-membered heterocyclic structure and therefore suitable to produce cyclopenta-fused pyrrole derivatives by the acid-catalyzed Nazarov reaction. These, on treatment with TFA, afforded 2,4-cis-disubstituted 2,3,4,5-tetrahydro-1H-cyclopenta[e] pyrrol-6-ones with high stereo-control. One of these Nazarov products was oxidized to the corresponding 4,5-dihydro-1H-cyclopenta[e]pyrrol-6-one derivative, thus obtaining an enantiopure key intermediate in the total synthesis of roseophilin.
New synthetic approach to cyclopenta-fused heterocycles based upon a mild nazarov reaction. 2. Further studies on the torquoselectivity
Prandi, Cristina,Ferrali, Alessandro,Guarna, Antonio,Venturello, Paolo,Occhiato, Ernesto G.
, p. 7705 - 7709 (2007/10/03)
Conjugated alkoxytrienes in which one of the double bonds is embedded in a heterocyclic moiety are obtained by the Pd-catalyzed coupling reaction of lactam- and lactone-derived vinyl triflates with α-alkoxydienylboronates. These compounds undergo a 4π ele
