790698-14-5

Upstream product

• 109613-59-4 (S)-1-(benzyloxy)but-3-en-2-ol 
• 79-08-3 bromoacetic acid 
• 2930-05-4 (S)-benzyl glycidyl ether 

Downstream Products

• 748770-49-2 4-(S)-benzyl-3-{2-[1-(S)-benzyloxymethyl-allyloxy]acetyl}oxazolidin-2-one 
• 130818-48-3 (+)-gigantecin 
• 790697-91-5 2-(S)-benzyloxymethyl-5-(S)-[1-(S)-methoxymethoxy-prop-2-ynyl]-2,5-dihydrofuran 
• 790698-02-1 1-(S)-[5-(S)-benzyloxymethyl-2,5-dihydrofuran-2-(S)-yl]-3-triisopropylsilyl-prop-2-yn-1-yl-methoxymethyl ether 
• 790698-01-0 {4-(S)-[1-(S)-benzyloxymethyl-allyloxy]-3-(S)-methoxymethoxy-hex-5-en-1-ynyl}triisopropylsilane 
• 790698-00-9 2-(S)-[1-(S)-benzyloxymethyl-allyloxy]-3-(S)-methoxymethoxy-5-triisopropylsilanyl-pent-4-yn-1-ol 
• 790697-99-3 4-(S)-benzyl-3-{2-(R)-[1-(S)-benzyloxymethyl-allyloxy]-3-(S)-hydroxy-5-triisopropylsilanyl-pent-4-ynoyl}oxazolidin-2-one 
• 790698-15-6 (S)-4-Benzyl-3-[(2R,3S)-2-((S)-1-benzyloxymethyl-allyloxy)-3-methoxymethoxy-5-triisopropylsilanyl-pent-4-ynoyl]-oxazolidin-2-one 
• 790698-08-7 4-(5-(S)-benzyloxymethyl-2,5-dihydrofuran-2-(S)-yl)-4-(S)-methoxymethoxy-1-[5-(R)-(1-(R)-methoxymethoxy-tridecyl)tetrahydrofuran-2-(R)-yl]but-2-yn-1-(R)-ol 
• 790698-09-8 2-(S)-benzyloxymethyl-5-(S)-{1-(S),4-(R)-bis-methoxymethoxy-4-[5-(R)-(1-(R)-methoxymethoxy-tridecyl)tetrahydrofuran-2-(R)-yl]but-2-ynyl}-2,5-dihydrofuran 
• 790698-11-2 3-[7-(5-(S)-{1-(S),4-(R)-bis-methoxymethoxy-4-[5-(R)-(1-(R)-methoxymethoxy-tridecyl)tetrahydrofuran-2-(R)-yl]butyl}tetrahydrofuran-2-(S)-yl)-2-(R)-(4-methoxybenzyloxy)hept-3-en-5-ynyl]-5-(S)-methyl-5H-furan-2-one 
• 790698-17-8 (S)-3-[(R)-7-((2R,5S)-5-{(1S,4R)-1,4-Bis-methoxymethoxy-4-[(2R,5R)-5-((R)-1-methoxymethoxy-tridecyl)-tetrahydro-furan-2-yl]-butyl}-tetrahydro-furan-2-yl)-2-(4-methoxy-benzyloxy)-heptyl]-5-methyl-5H-furan-2-one 
• 1328886-21-0 C₁₉H₂₅NO₅ 
• 1328886-20-9 C₂₄H₃₃NO₇ 

Relevant academic research and scientific papers

Formal synthesis of the bryostatin Northern Hemisphere: Asymmetric synthesis of the B ring and C1-C9 fragment

A formal synthesis of the top half fragment of bryostatin 11 has been developed. Stereoselective construction of the B ring was achieved by using a ring-closing metathesis reaction in conjunction with asymmetric glycolate alkylation. Furthermore, the C1-C9 fragment was synthesized by Brown allylation, chelation-controlled aldol condensation, and Saksena-Evans reduction to construct all stereogenic centers. Georg Thieme Verlag Stuttgart - New York.

Enantioselective total synthesis of (+)-gigantecin: Exploiting the asymmetric glycolate aldol reaction

The enantioselective synthesis of the potent, selective, cytotoxic, annonaceous acetogenin, (+)-gigantecin, has been completed. An asymmetric glycolate aldol serves to establish the stereocenters at C13,14 and at C21,22. A Carreira asymmetric acetylide ad