79092-51-6

Upstream product

• 38870-89-2 Methoxyacetyl chloride 
• 141422-88-0 [(E)-3-Phenyl-prop-2-en-(Z)-ylideneamino]-acetic acid 4-nitro-benzyl ester 
• 14371-10-9 (E)-3-phenylpropenal 
• 7352-64-9 glycine 4-nitrobenzyl ester 

Downstream Products

• 79092-53-8 [(3S,4R)-3-Methoxy-2-oxo-4-((E)-3-oxo-but-1-enyl)-azetidin-1-yl]-acetic acid 4-nitro-benzyl ester 
• 79092-53-8 [(3S,4R)-3-Methoxy-2-oxo-4-((Z)-3-oxo-but-1-enyl)-azetidin-1-yl]-acetic acid 4-nitro-benzyl ester 
• 79092-56-1 Potassium; (6R,7S)-7-methoxy-3-methyl-8-oxo-1-aza-bicyclo[4.2.0]octa-2,4-diene-2-carboxylate 
• 79092-54-9 (2S,3R,6S,7R)-3-Hydroxy-7-methoxy-3-methyl-8-oxo-1-aza-bicyclo[4.2.0]oct-4-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 79092-55-0 (6R,7S)-7-Methoxy-3-methyl-8-oxo-1-aza-bicyclo[4.2.0]octa-2,4-diene-2-carboxylic acid 4-nitro-benzyl ester 
• 141422-78-8 p-nitrobenzyl 3-methoxy-4-tosyloxymethyl-2-azetidinon-1-ylacetate 
• 141422-84-6 p-nitrobenzyl 3-ethylthio-7-methoxy-1-dethia-2-thia-3-cephemcarboxylate 
• 141422-85-7 (6S,7S)-3-Mercapto-7-methoxy-8-oxo-4-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 141422-77-7 ((2R,3S)-2-Hydroxymethyl-3-methoxy-4-oxo-azetidin-1-yl)-acetic acid 4-nitro-benzyl ester 
• 79092-52-7 ((2S,3S)-2-Formyl-3-methoxy-4-oxo-azetidin-1-yl)-acetic acid 4-nitro-benzyl ester 

Relevant academic research and scientific papers

ANIONIC 4+2 CYCLIZATION ROUTE TO 3-SULFUR SUBSTITUTED ISOCEPHEM ANALOGS

Four different isocephem analogs have been synthesized.The key step in the construction of the bicyclic ring involves an anionic 4+2 cyclization.The lithio derivative obtained from a suitably protected N-carboxymethyl-2-azetidinone was condensed with carb

TOTAL SYNTHESIS OF THE 1-CARBAPEN-2-EM AND 1-CARBACEPHA-1,3-DIENE SYSTEMS

The total synthesis of the 1-carbapen-2-em and 1-carbacepha-1,3-diene systems via an internal aldol condensation of enolisable oxo derivatives of azetidinones is described.