79106-37-9

Basic information

• Product Name: 1-<2-oxo-2-(3,4-dimethoxyphenyl)-1-methylethyl>-4-(1,2,3,4-tetrahydro-2-oxo-1-quinazolinyl)piperidine
• Synonyms: 1-<2-oxo-2-(3,4-dimethoxyphenyl)-1-methylethyl>-4-(1,2,3,4-tetrahydro-2-oxo-1-quinazolinyl)piperidine
• CAS NO: 79106-37-9
• Molecular Weight: 423.512
• Mol File: 79106-37-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-<2-oxo-2-(3,4-dimethoxyphenyl)-1-methylethyl>-4-(1,2,3,4-tetrahydro-2-oxo-1-quinazolinyl)piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-<2-oxo-2-(3,4-dimethoxyphenyl)-1-methylethyl>-4-(1,2,3,4-tetrahydro-2-oxo-1-quinazolinyl)piperidine(79106-37-9)
• EPA Substance Registry System: 1-<2-oxo-2-(3,4-dimethoxyphenyl)-1-methylethyl>-4-(1,2,3,4-tetrahydro-2-oxo-1-quinazolinyl)piperidine(79106-37-9)

Safety Data

• Hazardous Substances Data: 79106-37-9(Hazardous Substances Data)

Upstream product

• 1835-05-8 2-bromo-1-(3,4-dimethoxyphenyl)propan-1-one 
• 79098-77-4 1,3-dihydro-1-[piperidin-4-yl]-1H-3,4-dihydroquinazolin-2-one 
• 76857-06-2 1-benzylspiro-4'-one 
• 79098-91-2 1-benzyl-4-(1,2,3,4-tetrahydro-2-oxo-1-quinazolinyl)piperidine 
• 28144-70-9 anthranilic acid amide 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 79098-90-1 1-benzyl-4-[N-(o-aminomethylphenyl)-amino]-piperidine 

Downstream Products

• 79106-38-0 1-[3-(3,4-Dimethoxyphenyl)-3-hydroxypropyl-2-]-4-[3,4-dihydro-2(1H)-quinazolinon-1-yl]-piperidine 
• 98754-24-6 threo-1-<2-acetoxy-2-(3,4-dimethoxyphenyl)-1-methylethyl>-4-(1,2,3,4-tetrahydro-2-oxo-1-quinazolinyl)piperidine 
• 79106-38-0 threo-1-<2-hydroxy-2-(3,4-dimethoxyphenyl)-1-methylethyl>-4-(1,2,3,4-tetrahydro-2-oxo-1-quinazolinyl)piperidine 

Relevant articles and documents

Synthesis of 1- and 3-(1-substituted 4-piperidinyl)-1,2,3,4-tetrahydro-2-oxoquinazolines as potential antihypertensive agents

A series of 1- and 3-(1-substituted 4-piperidinyl)-1,2,3,4-tetrahydro-2-oxoquinazolines were synthesized and tested for antihypertensive activity. Among the compounds tested, 1-(2-hydroxy-2-phenethyl)-4-(1,2,3,4-tetrahydro-2-oxo-3-quinazolinyl) piperidine derivatives were generally the most effective in lowering blood pressure in the spontaneous hypertensive rat model. Of these, 1-[2-(4-chlorophenyl)-2-hydroxyethyl]-4-(1,2,3,4-tetrahydro-2-oxo-3- quinazolinyl)piperidine (KF5908) seemed the most promising.