79110-06-8

Upstream product

• 23082-50-0 2'-chloro-5'-nitroacetophenone 
• 62-53-3 aniline 
• 79110-05-7 1-(2-fluoro-5-nitrophenyl)ethanone 
• 14150-94-8 3,5-dinitro-1-methyl-2-pyridone 
• 7294-89-5 4-(phenylamino)pent-3-en-2-one 
• 445-27-2 2'-Fluoroacetophenone 

Relevant academic research and scientific papers

Synthesis of functionalized 4-nitroanilines by ring transformation of dinitropyridone with enaminones

2-Functionalized 4-nitroanilines were readily synthesized by ring transformation using 3,5-dinitro-2-pyridone and enaminones prepared from 1,3-dicarbonyl compounds and amines. Modification of the amino group and the ortho-position could be achieved by sim

The Preparation of Some 2-Nitroacridines and Related Compounds

The reaction of 2-fluoro-5-nitrobenzaldehyde with a wide variety of arylamines gives, in general, mixtures of the corresponding 2-arylamino-5-nitrobenzaldehydes and their related anils.Both aldehydes and anils readily underwent acid-catalysed cyclization to give the corresponding 2-nitroacridines.The effect of substituent on the rate of cyclization of these aldehydes and of some related anilino-benzaldehydes and -acetophenones has been studied in trifluoroacetic acid solution by means of 1H n.m.r. spectroscopy.A solution of 2-(N-methylanilino)-5-nitrobenzaldehydein trifluoroacetic acid appears to contain a substituted acridinium ion; treatment of this solution with alkali gave 10-methyl-2-nitroacridone. 1H n.m.r. data for a wide variety of substituted 2-nitroacridines are discussed.