Cas 791101-25-2,{(4R,5S)-5-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-methanol

791101-25-2

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Basic information

Product Name: {(4R,5S)-5-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-methanol
Synonyms: {(4R,5S)-5-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-methanol
CAS NO:791101-25-2
Molecular Formula:
Molecular Weight: 414.617
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: {(4R,5S)-5-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-methanol(CAS DataBase Reference)
NIST Chemistry Reference: {(4R,5S)-5-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-methanol(791101-25-2)
EPA Substance Registry System: {(4R,5S)-5-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-methanol(791101-25-2)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
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Hazardous Substances Data: 791101-25-2(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 791101-25-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,9,1,1,0 and 1 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 791101-25:
(8*7)+(7*9)+(6*1)+(5*1)+(4*0)+(3*1)+(2*2)+(1*5)=142
142 % 10 = 2
So 791101-25-2 is a valid CAS Registry Number.

791101-25-2Upstream product

791101-25-2Downstream Products

603040-23-9 C₂₄H₃₂O₄Si

791101-25-2Relevant academic research and scientific papers

Compositions And Methods Comprising Analogues Of Radicicol A

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Page/Page column 45, (2010/09/18)

Disclosed are novel analogues of the natural product radicicol A of formulae I, .Ia, pi, Ha, lib and HI, pharmaceutical compositions comprising the compounds. The compounds of the invention are kinase and phosphatase inhibitors and find utility in the tre

Synthesis of a Resorcylic Acid Lactone (RAL) library using fluorous-mixture synthesis and profile of its selectivity against a panel of kinases

Jogireddy, Rajamalleswaramma,Dakas, Pierre-Yves,Valot, Gaelle,Barluenga, Sofia,Winssinger, Nicolas

supporting information; experimental part, p. 11498 - 11506 (2010/05/02)

A library of resorcylic acid lactones (RAL) containing a cis-enone moiety targeting kinases bearing a cysteine residue within the ATP-binding pocket was prepared using a fluorous-mixture synthesis and evaluated against a panel of 19 kinases thus providing important structure-activity trends. Two new analogues were then profiled for their selectivity against a panel of 402 kinases providing the broadest evaluation of this pharmacophores' selectivity.

Divergent syntheses of resorcylic acid lactones: L-783277, LL-Z1640-2, and hypothemycin

Dakas, Pierre-Yves,Jogireddy, Rajamalleswaramma,Valot, Gaelle,Barluenga, Sofia,Winssinger, Nicolas

supporting information; experimental part, p. 11490 - 11497 (2010/04/28)

The resorcylic acid lactones (RAL) are endowed with diverse biological activity ranging from transcription factor modulators (zearalenone and zearalenol) to HSP90 inhibitors (radicicol and pochonin D) and reversible (aigialomycin D) as well as irreversibl

Modular synthesis of radicicol A and related resorcylic acid lactones, potent kinase inhibitors

Dakas, Pierre-Yves,Barluenga, Sofia,Totzke, Frank,Zirrgiebel, Ute,Winssinger, Nicolas

, p. 6899 - 6902 (2008/09/18)

(Chemical Equation Presented) Short and sweet: A concise and modular synthesis of radicicol A and related resorcylic acid lactones using fluorous isolation technology and immobilized reagents is reported (see scheme, R F = C3H6

MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS

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Page/Page column 100, (2010/02/07)

The present invention provides compounds having formula (I), and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis, wherein R1 -R11, t, X, Y, Z, and n are as defined herein.

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