791814-94-3Relevant academic research and scientific papers
Azide based routes to tetrazolo and oxadiazolo derivatives of pyrrolobenzodiazepines and pyrrolobenzothiadiazepines
Hemming, Karl,Chambers, Christopher S.,Hamasharif, Muslih S.,Jo?o, Heidi,Khan, Musharraf N.,Patel, Nilesh,Airley, Rachel,Day, Sharn
, p. 7306 - 7317 (2016/02/03)
Tetrazolo- and 1,2,4-oxadiazolo-fused derivatives of the antitumour, antibiotic, DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepines and their pyrrolobenzothiadiazepine derivatives have been produced as analogues of a 1,2,3-triazolo-fused pyrrolobenzothiad
The synthesis of pyrrolo[1,2-b][1,2,5]benzothiadiazepines from 1,2-thiazine 1-oxides - Sulfonamide analogues of the pyrrolobenzodiazepine antitumour natural products
Hemming, Karl,Patel, Nilesh
, p. 7553 - 7556 (2007/10/03)
Pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) and the corresponding pyrrolobenzothiadiazepines (PBTDs) are attractive targets as natural and synthetic antitumour antibiotics and as non-nucleosidic reverse transcriptase inhibitors. A concise synthesis of the P
