791857-01-7Relevant academic research and scientific papers
Chiral phosphinooxazolidine ligands for palladium- and platinum-catalyzed asymmetric Diels-Alder reactions
Nakano, Hiroto,Takahashi, Kouichi,Okuyama, Yuko,Senoo, Chieko,Tsugawa, Natsumi,Suzuki, Yuichiro,Fujita, Reiko,Sasaki, Kazuo,Kabuto, Chizuko
, p. 7092 - 7100 (2004)
Cationic palladium (Pd)- and platinum (Pt)-phosphinooxazolidine catalysts 13a-c, 15a-d, 17a-c, and 19a-c were prepared from phosphinooxazolidine ligands 1-3, MCl2 (M = Pd and Pt), and counterions, and the activities of the catalysts in the asymmetric Diels-Alder (DA) reactions of cyclic or acyclic dienes with imide dienophiles were investigated. These catalysts demonstrated high levels of catalytic activity. The cationic Pd-POZ complex 13c provided particularly excellent enantioselectivity (98% ee) in the DA reactions of cyclopentadiene with acryloyl-, crotonyl-, and fumaroyl-1,3-oxazolidin-2-ones (20a-c).
