792-38-1Relevant academic research and scientific papers
Complexation of N′-[1-(2,4-dihydroxyphenyl)ethylidene] isonicotinohydrazide with lanthanide ions
Varam, Yuimi,Rajkumari, Lonibala
, p. 3552 - 3560 (2011)
The complexation of N′-[1-(2,4-dihydroxyphenyl)ethylidene] isonicotinohydrazide (DEH) with trivalent Pr, Nd, Gd, Tb, and Ho ions were studied employing potentiometric and spectroscopic techniques. The potentiometric studies carried out at different temper
Metal-binding hydrazone photoswitches for visible light reactivity and variable relaxation kinetics
Hall, Kacey C.,Franks, Andrew T.,McAtee, Rory C.,Wang, Michael S.,Lu, Vivian I.,Franz, Katherine J.
, p. 1604 - 1612 (2017/11/16)
The range of applications for photoswitching moieties is diverse, and the ability to design switches with variable photochemical and physical properties is consequently important for realizing their potential. Previously we reported on the photochromism o
Synthesis, antimycobacterial, antiviral, antimicrobial activities, and QSAR studies of isonicotinic acid-1-(substituted phenyl)-ethylidene/cycloheptylidene hydrazides
Judge, Vikramjeet,Ahuja, Munish,Narasimhan, Balasubramanian,Sriram, Dharmarajan,Yogeeswari, Perumal,De Clercq, Erik,Pannecouque, Christophe,Balzarini, Jan
, p. 1935 - 1952,18 (2020/07/30)
A series of isonicotinic acid-1-(substituted phenyl)-ethylidene/ cycloheptylidene hydrazide derivatives (1-12) was tested for their, in vitro antimycobacterial activity against Mycobacterium tuberculosis, and compound 2 was found to be more active than isoniazid. The antiviral screening results indicated that none of the tested compounds was active against a broad variety of DNA and RNA viruses at subtoxic concentrations, except compounds 8 and 10 that proved to be active against DNA viruses at concentrations close to their cytostatic potential. The synthesized compounds were also screened for their antimicrobial potential against S. aureus, B. subtilis, E. coli, C. albicans and A. niger, and the results indicated that compounds having Br, OCH3 and Cl groups were highly active. The multi-target QSAR models indicated the importance of lipophilic (log P) and topological parameters (3vv) in describing the antimicrobial activity.
Synthesis and initial in vitro evaluations of novel antioxidant aroylhydrazone iron chelators with increased stability against plasma hydrolysis
Hruskova, Katerina,Kovarikova, Petra,Bendova, Petra,Haskova, Pavlina,MacKova, Eliska,Stariat, Jan,Vavrova, Anna,Vavrova, Katerina,Simunek, Tomas
experimental part, p. 290 - 302 (2012/04/11)
Oxidative stress is known to contribute to a number of cardiovascular pathologies. Free intracellular iron ions participate in the Fenton reaction and therefore substantially contribute to the formation of highly toxic hydroxyl radicals and cellular injur
Synthesis, spectral, thermal, biological and 3D molecular modeling studies of oxidomolybdenum(V) and dioxidomolybdenum(VI) complexes derived from 2,4-dihydroxyacetophenone isonicotinoylhydrazone
Harikumaran Nair,Thankamani
experimental part, p. 1029 - 1039 (2011/06/19)
Synthesis of some novel oxidomolybdenum(V) and dioxidomolybdenum(VI) complexes with a Schiff base, (2,4-dihydroxy acetophenoneisonicotinoylhydrazone) (DAIH), derived from 2,4-dihydroxy acetophenone and isonicotinoylhydrazide are reported. The complexes ha
