79222-83-6Relevant academic research and scientific papers
Synthesis of antipyrine/pyridazinone hybrids and investigation of their in vivo analgesic and anti-inflammatory activities
Baytas, Sultan,Inceler, Nazan,Mavaneh, Khatereh Fattahpour,Uludag, Mecit Orhan,Abacioglu, Nurettin,Goekce, Mehtap
, p. 734 - 748 (2013/02/23)
Eleven antipyrine/pyridazinone hybrids were synthesized and evaluated for their in vivo analgesic and anti-inflammatory activities by p-benzoquinone- induced writhing test and carrageenan-induced paw edema model, respectively. The test results indicated t
Structure-activity relationships in a series of 8-substituted xanthines as A1-adenosine receptor antagonists
Strappaghetti, Giovannella,Corsano, Stefano,Barbaro, Roberta,Giannaccini, Gino,Betti, Laura
, p. 575 - 583 (2007/10/03)
A series of 8-substituted xanthines were synthesized and their affinity in vitro towards A1, A2A-adenosine receptors was evaluated by radioligand receptor binding assays. All compounds showed a greater affinity and selectivity toward
