79252-33-8Relevant academic research and scientific papers
SIMPLE AND CONDENSED β-LACTAMS. Part 6. A Synthesis of the p-Nitrobenzyl Esters of the Racemic Forms of the Carbapenem Antibiotics PS-5 and PS-6, and of Their 6-Epimers.
Fetter, Jozsef,Lempert, Karoly,Horvath, Zoltan,Kajtar-Peredy, Maria,Simig, Gyula,Hornyak, Gyula
, p. 3901 - 3932 (2007/10/02)
The p-nitrobenzyl esters of the racemic carbapenem antibiotics PS-5 and PS-6, and of their 6-epimers were synthesised starting with the trans (6a, 6c) and cis forms (6b, 6d) of ethyl 1-(2,4-dimethoxybenzyl)-4-oxo-2-azetidinecarboxylates, respectively.
A Short and Stereoselective Synthesis of the Carbapenem Antibiotic PS-5
Kametani, Tetsuji,Honda, Toshio,Nakayama, Atsushi,Sasakai, Yuko,Mochizuki, Tomoko,Fukumoto, Keiichiro
, p. 2228 - 2232 (2007/10/02)
The benzyl ester (3) and p-nitrobenzyl ester (PNB ester) (4) of the antibiotic PS-5 and the bis-protected PS-6 (5) were stereoselectively synthesised by application of the new carbon-carbon bond formation reaction at the C-4-position of 4-acetoxy-3-ethyl-
