79314-56-0Relevant academic research and scientific papers
Lanthanide Triflates as Water-Tolerant Lewis Acids. Activation of Commercial Formaldehyde Solution and Use in the Aldol Reaction of Silyl Enol Ethers with Aldehydes in Aqueous Media
Kobayashi, Shu,Hachiya, Iwao
, p. 3590 - 3596 (1994)
Lanthanide trifluoromethanesulfonates (triflates), especially ytterbium triflate (Yb(OTf)3), were found to be stable Lewis acids in water.In the presence of a catalytic amount of lanthanide triflate, formaldehyde in water solution (commercial formaldehyde
Iron(III) chloride as a water-compatible lewis acid for diastereoselective aldol reactions in water in the presence of a surfactant
Aoyama, Naohiro,Manabe, Kei,Kobayashi, Shu
, p. 312 - 313 (2007/10/03)
Diastereoselective aldol reactions of various aldehydes with silicon enolates in water have been successfully carried out using iron(III) chloride and a surfactant. Contrary to previous understanding, iron(III) chloride has been shown to be a water-compat
Rare Earth Metal Complexes as Water-Tolerant Lewis Acid Catalysts in Organic Synthesis
Kobayashi,Hashiya,Ishitani,Moriwaki,Nagayama
, p. 193 - 202 (2007/10/03)
Rare earth metal triflates are stable in aqueous media and can act as Lewis acid catalysts in several carbon-carbon bond forming reactions. This article describes some of these reactions; aldol and Mannich-type reactions in aqueous solution, and Friedel-Crafts acylations and Fries rearrangement in organic solvents. The reactions proceeded smoothly in the presence of a catalytic amount of the triflate under mild conditions. Moreover, the catalysts could be recovered after the reactions were completed and could be reused.
