79317-63-8

Upstream product

• 186581-53-3 diazomethane 
• 2572-40-9 (o-carboxyphenyl)diphenylphosphine oxide 
• 79932-99-3 methyl 2-diphenylphosphinobenzoate 
• 4397-55-1 phthalic monoacid monomethyl ester chloride 
• 4376-18-5 Monomethyl phthalate 
• 71-43-2 benzene 
• 5931-53-3 Diphenyl-o-tolylphosphin 
• 1079-66-9 chloro-diphenylphosphine 
• 6840-26-2 diphenyl-o-tolyl-phosphine oxide 
• 932-31-0 ortho-tolylmagnesium bromide 
• 610-94-6 2-bromobenzoic acid methyl ester 
• 4559-70-0 Diphenylphosphine oxide 

Downstream Products

• 1071983-26-0 2-(diphenylphosphoryl)benzamide 
• 80750-50-1 2-(1-hydroxy-1-methylethyl)phenyl(diphenyl)phosphine oxide 

Relevant academic research and scientific papers

Palladium-catalyzed C–P bond activation of aroyl phosphine oxides without the adjacent “anchoring atom”

A novel palladium-catalyzed decarbonylation of aroyl phosphine oxides to prepare phosphine oxides from carboxylic acids is developed. Without the adjacent “anchoring atom”, the challenging C–P bond activation is achieved in high selectivity. The disclosure of this reaction provides a new example of C–P bond activation and helps to extend the understanding of the property of C–P bond.

Visible-Light-Induced Nickel-Catalyzed P(O)-C(sp2) Coupling Using Thioxanthen-9-one as a Photoredox Catalysis

An efficient method has been developed for photocatalytic P(O)-C(sp2) coupling of (hetero)aryl halides with H-phosphine oxides or H-phosphites under the irradiation of visible light or sunlight. The thioxanthen-9-one/nickel dual catalysis mediates this ph

Reductive phosphine-mediated ligation of nitroxyl (HNO)

Nltroxyl (HNO) demonstrates a unique chemical and biological profile compared to nitric oxide (NO). Phosphorus NMR studies reveal that HNO reacts with triarylphosphines to give the corresponding phosphine oxide and aza-ylide. In the presence of a properly situated electrophilic ester, the aza-ylide undergoes a Staudinger ligation to yield an amide with the nitrogen atom being derived from HNO. These results define new HNO reactivity and provide the basis of new HNO detection methods.

Homolytic substitution at phosphorus for the synthesis of alkyl and aryl phosphanes

(Chemical Equation Presented) A transition-metal-free radical phosphonation using Me3SnPPh2 and the less toxic Me 3SiPPh2 is reported. These readily available reagents react highly efficiently with primary and secondary alkyl radicals. Moreover, aryl radicals and tertiary alkyl radicals are phosphonated with Me 3SnPPh2 (see scheme; R = aryl, alkyl, vinyl; X = 1, Br, OC(S)imidazolyl). DFT calculations provide insights into the mechanism of the reaction.