79323-29-8Relevant academic research and scientific papers
Ruthenium-Catalyzed Dehydrogenation Through an Intermolecular Hydrogen Atom Transfer Mechanism
Huang, Lin,Bismuto, Alessandro,Rath, Simon A.,Trapp, Nils,Morandi, Bill
supporting information, p. 7290 - 7296 (2021/03/01)
The direct dehydrogenation of alkanes is among the most efficient ways to access valuable alkene products. Although several catalysts have been designed to promote this transformation, they have unfortunately found limited applications in fine chemical synthesis. Here, we report a conceptually novel strategy for the catalytic, intermolecular dehydrogenation of alkanes using a ruthenium catalyst. The combination of a redox-active ligand and a sterically hindered aryl radical intermediate has unleashed this novel strategy. Importantly, mechanistic investigations have been performed to provide a conceptual framework for the further development of this new catalytic dehydrogenation system.
General, Mild, and Selective Method for Desaturation of Aliphatic Amines
Chuentragool, Padon,Parasram, Marvin,Shi, Yi,Gevorgyan, Vladimir
supporting information, p. 2465 - 2468 (2018/02/28)
A novel method for desaturation of aliphatic amines into enamines as well as allylic and homoallylic amines has been developed. This general protocol operates via putative aryl hybrid Pd-radical intermediates, which combine the signature features of radic
Effects of Substitution on Nitrogen on Barriers to Rotation of Amides. 2 - Evaluation of the Importance of Resonance Effects
Pinto, B. Mario,Szarek, Walter A.,Grindley, T. Bruce
, p. 676 - 692 (2007/10/02)
Analogs of N-acetyl- and N-benzoyl-azacyclohex-2-enes having an oxygen atom, a methylene-d2 group or a carbonyl group in place of the C-4 methylene group have been synthesized.The amide rotational barriers in these compounds have been measured by the tota
Synthesis of 4-Acyl-2,3-dihydro-4H-1,4-oxazines
Nicola, Massimo,Gaviraghi, Giovanni,Pinza, Mario,Pifferi, Giorgio
, p. 825 - 828 (2007/10/02)
The synthesis of 4-acyl-2,3-dihydro-4H-1,4-oxazines (6a-h) via acid dehydration of 4-acyl 2- and 3-morpholinols is described.During dehydration of 2-morpholinols 3d,e, N-alkylisoquinolones 7a-e were also isolated.
