79370-15-3

Upstream product

• 67-56-1 methanol 
• 2844-17-9 4-(dimethylamino)-4'-cyanostilbene 
• 889-37-2 N,N-dimethyl-4-((phenylimino)methyl)aniline 
• 14295-52-4 4-(diethyoxyphosphorylmethyl)benzoic acid methyl ester 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 104-85-8 para-methylbenzonitrile 

Downstream Products

• 1345418-31-6 4-[(4-{(E)-2-[4-(dimethylamino)phenyl]ethenyl}benzoyl)amino]-1-methyl-N-[1-methyl-5-({[2-(4-morpholinyl)ethyl] amino}carbonyl)-1H-pyrrol-3-yl]-1H-pyrrole-2-carboxamide 

Relevant academic research and scientific papers

Amide isosteres in structure-activity studies of antibacterial minor groove binders

Antibacterial minor groove binders related to the natural product, distamycin, are development candidates for novel antibiotics. Alkenes have been found to be effective substitutes for the isosteric amide links in some positions and alkyl groups larger th

Aromatic Phosphines with Second Order Substituents, XVI. - Phenylogous PO-activated Olefination: Synthesis of 4'-Donator Substituted 4-(Diphenylphosphinyl)stilbenes

Being a -M substituent, the 4-diphenylphosphinyl group acidifies the methyl group of toluene to a similar degree as a 4-cyano group.The carbanion formed by deprotonation reacts with N-benzylidene anilines to yield 4-(diphenylphosphinyl)stilbenes.In these, UV-spectroscopically the phosphorus on the one hand behaves like a -M substituent, on the other hand it acts as a barrier to through-conjugation.