79434-38-1

Upstream product

• 79386-37-1 2-<(2'RS,3'RS)-3'-hydroxy-5'-oxotetrahydrofuran-2'-yl>-5-methoxy-1,4-naphthoquinone 
• 79386-30-4 3-bromo-5-hydroxy-2-(3'-methoxycarbonylpropyl)-1,4-naphthoquinone 
• 79386-36-0 2-(1',2'-dihydroxy-3'-methoxycarbonylpropyl)-1,4,5-trimethoxynaphthalene 
• 79386-33-7 1,4,5-trimethoxy-2-(3'-methoxycarbonylpropyl)naphthalene 
• 79386-31-5 3-bromo-5-methoxy-2-(3'-methoxycarbonylpropyl)-1,4-naphthoquinone 
• 52431-65-9 3-Bromojuglone 
• 481-39-0 5-hydroxynaphtho-1,4-quinone 
• 3588-80-5 5-methoxynaphthalen-1-ol 
• 184899-96-5 C₁₇H₁₄O₅ 
• 79386-34-8 trans-1,4,5-trimethoxy-2-(3'-methoxycarbonylprop-1'-enyl)naphthalene 
• 79386-32-6 3-bromo-1,4,5-trimethoxy-2-(3'-methoxycarbonylpropyl)naphthalene 
• 79386-35-9 2-<(2'RS,3'RS)-3'-hydroxy-5'-oxotetrahydrofuran-2'-yl>-1,4,5-trimethoxynaphthalene 
• 86309-89-9 2,2-Dimethylnaphtho<1,8-de><1,3>dioxin-6-ol 
• 683227-68-1 methyl 4-(1-hydroxy-5-methoxynaphthalen-2-yl)-3-methoxy-4-oxobutyrate 

Relevant academic research and scientific papers

The Synthesis of (+/-)-Juglomycin A and (+/-)-Juglomycin B, Racemates of two Isomeric Naturally Occurring Naphthoquinonoid Antibiotics

Syntheses of diastereoisomeric 5-hydroxy-2-(4'-hydroxy-γ-butyrolacton-5'-yl)-1,4-naphthoquinones (1) and (2) and their 5-deoxy-analogues (3) and (4) are described.The stereochemistries of the latter, being defined through unambiguous synthesis, permit the assignment of the configurations of (1) and (2) (which were obtained from a single precursor) and also those of the natural products, juglomycins A and B.

Efficient Synthesis of (±)-Juglomycin A

(±)-Juglomycin A has been synthesized in 8 steps from 1-hydroxy-5-methoxynaphthalene.