3588-80-5

Usage

Uses

Used in Organic Synthesis:
5-Methoxy-1-naphthalenol is used as a key intermediate for the synthesis of various organic compounds. Its chemical structure allows it to participate in a wide range of reactions, making it a versatile building block in the creation of complex molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 5-Methoxy-1-naphthalenol is used as a starting material for the development of new drugs. Its unique chemical properties enable the synthesis of novel drug candidates with potential therapeutic applications.
Used in Chemical Research:
5-Methoxy-1-naphthalenol is also employed in chemical research as a model compound to study various reaction mechanisms and to develop new synthetic methodologies. Its reactivity and structural features make it an ideal candidate for exploring new chemical pathways and understanding fundamental reaction principles.
Used in Flavor and Fragrance Industry:
Due to its distinct chemical structure, 5-Methoxy-1-naphthalenol can be used as a component in the development of new fragrances and flavors. Its unique scent and taste properties can contribute to the creation of innovative and appealing products in the flavor and fragrance market.
Used in Dye and Pigment Industry:
5-Methoxy-1-naphthalenol's brown solid form and chemical properties make it suitable for use in the dye and pigment industry. It can be employed in the synthesis of new dyes and pigments, contributing to the development of a diverse range of colorants for various applications, such as textiles, plastics, and coatings.

Upstream product

• 83-56-7 1,5-dihydroxynaphthalene 
• 77-78-1 dimethyl sulfate 
• 67-56-1 methanol 
• 64725-89-9 1-benzoyloxy-5-methoxy naphthalene 
• 10075-63-5 1,5-dimethoxynaphthalene 
• 33892-75-0 5-Methoxy-1-tetralone 
• 5123-13-7 5,5-dimethyl-2-phenyl-1,3,2-dioxaborinane 

Downstream Products

• 31461-16-2 2-(8-hydroxy-4-methoxy-[1]naphthoyl)-benzoic acid 
• 10075-63-5 1,5-dimethoxynaphthalene 
• 60963-09-9 1-(2,6-Dichloro-4-nitro-phenoxy)-5-methoxy-naphthalene 
• 79786-98-4 1-Hydroxy-5-methoxynaphthalin-2-carbonsaeure 
• 128462-00-0 C₃₁H₂₈O₇ 
• 128461-99-4 C₃₁H₂₈O₇ 
• 61539-67-1 5-methoxy[1,2]naphthoquinone 
• 4923-61-9 5-methoxynaphthoquinone 
• 481-39-0 5-hydroxynaphtho-1,4-quinone 
• 101303-83-7 8-Hydroxy-4-methoxy-1,2-naphthochinon 
• 37721-75-8 tetrabromo-p-cresol 
• 110387-91-2 4-nitro-5-methoxy-1-hydroxynaphthalene 
• 110387-90-1 1-hydroxy-5-methoxy-2-nitronaphthalene 
• 64725-89-9 1-benzoyloxy-5-methoxy naphthalene 

Relevant academic research and scientific papers

Isomerization of 7-oxabenzonorbornadienes into naphthols catalyzed by [RuCl2(CO)3]2

(Chemical Equation Presented) Ruthenium-catalyzed isomerization of 7-oxanorbornadienes into naphthols was investigated. Among the various ruthenium catalysts tested, [RuCl2(CO)3]2 gave the highest yields in the isomerizati

A nickel catalyst for the addition of organoboronate esters to ketones and aldehydes

A Ni(cod)2/IPr catalyst promotes the intermolecular 1,2-addition of arylboronate esters to unactivated aldehydes and ketones. Dlaryl, alkyl aryl, and dialkyl ketones show good reactivity under mild reaction conditions (3) with aryl ether substrates. A Ni(0)/Ni(II) catalytic cycle initiated by the oxidative cyclization of the carbonyl substrate Is proposed.

An efficient method for demethylation of aryl methyl ethers

A new efficient method for demethylation of aryl methyl ethers using iodocyclohexane in DMF under reflux condition is described.

Regioselective Monomethylation of Unsymmetrical Naphthalenediols with Methanolic HCl

Treatment of naphthalene-1,3-diol and naphthalene-1,7-diol with methanol containing dry hydrogen chloride at room temperature gives exclusively 3-methoxy-1-naphthol and 7-methoxy-1-naphthol, respectively.Of the other two unsymmetrical naphthalenediols, the 1,2-isomer was unreactive and the 1,6-isomer gave a mixture of regioisomers under the same conditions.Two symmetrical diols (the 1,5- and 2,7-isomers) examined by the same procedure gave the monomethyl ethers in 60-70percent yields.

HALOGENATION REGIOSELECTIVE EN SERIE AROMATIQUE-II CHLORATION DES NAPHTOLS ET LEURS ETHERS A L'AIDE DE REACTIFS METTANT EN JEU DES INTERACTIONS DU TYPE DONNEUR-ACCEPTEUR

The regispecific chlorination of naphtols by hexachlorocyclohexadienones as selective chlorinating reagents is described.The selectivity attained is better than that which we have obtained with phenol derivatives and confirms the importance of the donor-acceptor interaction between the reagent and the naphthol during the chlorination.

PHOTO FRIES REARRANGEMENTS OF 1-NAPHTHYL ESTERS IN THE SYNTHESIS OF 2-ACYLNAPHTHOQUINONES

The photo Fries rearrangements of esters of 1-naphthol and 5-methoxy-1-naphthol to the corresponding 1-hydroxy-2-acylnaphthalenes have been carried out.The best yield (70percent) was obtained by irradiating 5-methoxy-1-naphthyl acetate in ethyl acetate.By contrast the yield from 1-naphthyl acetate under similar conditions was 40percent.Oxidation of 1-hydroxy-5-methoxy-2-naphthyl cyclohexyl ketone with thallium trinitrate gave the corresponding 1,4-quinone.These results provide a method for the regioselective synthesis of tricyclic analogues of adriamycinone.