79465-83-1

Basic information

• Product Name: Dimethyl-(2S, 3aR, 8aS)-8-acetyl-1,2,3,3a,8a-hexahydropyrrolo[2,3]indol-1,2-dicarboxylate
• Synonyms: Pyrrolo[2,3-b]indole-1,2(2H)-dicarboxylic acid, 8-acetyl-3,3a,8,8a-tetrahydro-, dimethyl ester, (2alpha,3abeta,8abeta)-;Dimethyl-8-acetyl-hexahydropyrrolo[2,3]indol-1,2-dicarboxylate
• CAS NO: 79465-83-1
• Molecular Formula: C₁₆H₁₈N₂O₅
• Molecular Weight: 0
• Mol File: 79465-83-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Dimethyl-(2S, 3aR, 8aS)-8-acetyl-1,2,3,3a,8a-hexahydropyrrolo[2,3]indol-1,2-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Dimethyl-(2S, 3aR, 8aS)-8-acetyl-1,2,3,3a,8a-hexahydropyrrolo[2,3]indol-1,2-dicarboxylate(79465-83-1)
• EPA Substance Registry System: Dimethyl-(2S, 3aR, 8aS)-8-acetyl-1,2,3,3a,8a-hexahydropyrrolo[2,3]indol-1,2-dicarboxylate(79465-83-1)

Safety Data

• Hazardous Substances Data: 79465-83-1(Hazardous Substances Data)

Usage

Chemical Properties

Colourless crystals

Upstream product

• 66377-68-2 N_b-methoxycarbonyl-DL-tryptophan methyl ester 
• 108-24-7 acetic anhydride 
• 67811-38-5 DL-(2β,3aα,8aα)-1,2,3,3a,8,8a-hexahydro-1,2-dimethoxycarbonylpyrrolo<2,3-b>indole 

Downstream Products

• 107447-06-3 trans-1-isobutyl-7-methoxy-3-methoxycarbonyl-1,2,3,4-tetrahydro-β-carboline 
• 107447-05-2 (1S,3S)-methyl-1-isobutyl-7-methoxy-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylate 
• 107462-41-9 (1S,3S)-2-((S)-1-Benzyloxycarbonyl-pyrrolidine-2-carbonyl)-1-isobutyl-7-methoxy-2,3,4,9-tetrahydro-1H-β-carboline-3-carboxylic acid methyl ester 
• 107447-04-1 (S)-methyl 2-amino-3-(6-methoxy-1H-indol-3-yl)propanoate 
• 154-07-4 2-amino-3-(5-chloro-1H-indol-3-yl)propanoic acid 
• 6525-46-8 5-nitro-L-tryptophan 
• 6525-46-8 5-nitro-D-tryptophan 
• 93299-38-8 5-bromo-D-tryptophan methyl ester 
• 6548-09-0 5-bromo-L-tryptophan 
• 154-07-4 5-chloro-D-tryptophan 

Relevant articles and documents

CYCLIC TAUTOMERS OF TRYPTOPHANS AND TRYPTAMINES-4; SYNTHESIS OF CYCLIC TAUTOMERS OF TRYPTOPHANS AND TRYPTAMINES

Nb-Methoxycarbonyltryptophan methyl ester (DL- and L-13) was cyclized to the corresponding trans cyclic tautomer (14) in excellent yield in various acids such as 85percent phosphoric acid or trifluoroacetic acid.The cis cyclic tautomer (15) was formed as the less stable and kinetically controlled product and converted to the more stable trans isomer (14) under the reaction condition.The trans isomer (14) was reverted to 13 on treatment with 10percent sulfuric acid in methanol.Other tryptophan and tryptamine derivatives (6 and 19a) also cyclized to the corresponding cyclic tautomers in similar acidic media.