79491-36-4Relevant academic research and scientific papers
Domino Synthesis of 4-Alkylidene-3,4-dihydro-2H-pyrroles from Homopropargyl Sulfonamides and Aldehydes
Amemiya, Sho,Takahashi, Yui,Tsubouchi, Akira,Saito, Akio
, p. 5717 - 5724 (2021/10/30)
Abstract: We describe a domino synthesis of 4-alkylidene-3,4-dihydro-2H-pyrroles from aryl-substituted homopropargyl sulfonamides and aldehydes promoted by cheap and easy-to-handle TsOH ? H2O. The present reactions proceed through cyclocondensation of α-sulfonamidoethyl-α,β-enone intermediates, which are formed by ring-cleavage of 3-acylpyrrolidines corresponding to aza-Prins cyclized intermediates. By controlling the conditions, 3-acylpyrrolidines can be obtained.
Synthesis and photoisomerization of rhodopsin-based molecular switches
Blanco-Lomas, Marina,Campos, Pedro J.,Sampedro, Diego
, p. 6328 - 6334,7 (2020/09/16)
A new family of switches based on a rhodopsin chromophore is presented. These new photoswitches fulfil most of the required features for an efficient switch to be used in practical applications. The synthetic route is simple and versatile and enables substituents capable of acting as anchoring points to be incorporated. Also, substitution can be used to fine tune the switches' properties. The photostationary state can be reached easily by using low-energy light compatible with complex environments. Thermal reset allows these switches to operate through on/off cycles.
Bischler-Napieralski Reaction of N-(4-Aryl-4-hydroxybutyl)benzamides: Synthesis and X Ray Structure of (E)-3-Arylmethylidene-4,5-dihydro-3H-pyrroles
Browne, Elaine J.,Skelton, Brian W.,White, Allan H.
, p. 897 - 904 (2007/10/02)
The N-(4-aryl-4-hydroxybutyl)benzamides (3a,b) have been cyclized under Bischler-Napieralski conditions to the 3-arylmethylidene-4,5-dihydro-3H-pyrroles (4a,b).These products are consistent with the formation of N-(4-arylbut-3-enyl)benzamide intermediates
