79492-26-5

Usage

Uses

Used in Scientific Research:
3,4-dihydroisoquinolin-2(1H)-amine hydrochloride is used as a research chemical for studying its interactions with biological systems. Its properties and behavior in various contexts can provide valuable insights into its potential applications and effects.
Used in Medical Research:
In the medical field, 3,4-dihydroisoquinolin-2(1H)-amine hydrochloride is used as a research compound to explore its potential in the development of new therapeutic agents. Its chemical structure and reactivity may contribute to the creation of novel drugs or drug delivery systems.
Used in Synthesis of Complex Compounds:
3,4-dihydroisoquinolin-2(1H)-amine hydrochloride is used as a building block or intermediate in the synthesis of more complex organic compounds. Its unique structure and reactivity make it a valuable component in the creation of advanced chemical entities for various applications, including pharmaceuticals and materials science.

Upstream product

• 17721-96-9 2-nitroso-1,2,3,4-tetrahydroisoquinoline 
• 79492-47-0 N-(t-butyloxycarbonyl)amino-1,2,3,4-tetrahydroisoquinoline 
• 38256-56-3 1-(2-bromo-ethyl)-2-bromomethyl-benzene 
• 91-21-4 1,2,3,4-tetrahydroisoquinoline 

Downstream Products

• 79492-46-9 N-(3,4,5-trimethoxybenzylidene)amino-1,2,3,4-tetrahydroisoquinoline 
• 79492-44-7 2-benzylideneamino-1,2,3,4-tetrahydroisoquinoline 
• 79492-44-7 N-benzylideneamino-1,2,3,4-tetrahydroisoquinoline 
• 79492-41-4 N-(p-hydroxybenzylidene)amino-1,2,3,4-tetrahydroisoquinoline 
• 79492-38-9 N-(p-methoxybenzylidene)amino-1,2,3,4-tetrahydroisoquinoline 
• 79492-43-6 N-(o-hydroxybenzylidene)amino-1,2,3,4-tetrahydroisoquinoline 
• 79492-42-5 N-(m-hydroxybenzylidene)amino-1,2,3,4-tetrahydroisoquinoline 
• 79492-39-0 N-(m-methoxybenzylidene)amino-1,2,3,4-tetrahydroisoquinoline 
• 374567-13-2 (3,4-dihydro-1H-isoquinolin-2-yl)-carbamic acid 4-tert-butoxycarbonylamino-phenyl ester 
• 19350-92-6 2-p-Toluenesulfonamido-1,2,3,4-tetrahydroisoquinoline 
• 79492-40-3 N-(o-methoxybenzylidene)amino-1,2,3,4-tetrahydroisoquinoline 
• 79492-45-8 N-(p-nitrobenzylidene)amino-1,2,3,4-tetrahydroisoquinoline 
• 79492-45-8 2-(p-nitrobenzylideneamino)-1,2,3,4-tetrahydroisoquinoline 

Relevant academic research and scientific papers

Hydrosulfite Reduction of N-Nitroso-1,2,3,4-tetrahydroisoquinolines and Oxidation of N-Amino-1,2,3,4-tetrahydroisoquinolines

The sodium hydrosulfite reduction of N-nitroso-1,2,3,4,-tetrahydroisoquinolines (5) does not result in the loss of nitrogen and leads to the corresponding hydrazine 6 which upon oxidation with mercuric oxide in ethanol at 62 deg gives the hexahydrotetrazine 7 in 39percent yield.Treatment of the n-tosyl derivative of 6 with base affords 7 in nearly quantitative yield.Oxidation of 6 in 1-butanol at 95 deg results in the formation of a complex product mixture from which only one component, 1,1'-azobis-3,4-dihydroisoquinoline (8) could be isolated.Surprisingly the sodium hydrosulfite reduction of 2-nitroso-3-phenyl-1,2,3,4-tetrahydroisoquinoline (15) also failed to proceed with loss of nitrogen and yields the corresponding hydrazine 16.However, 16 was cleanly oxidized by mercuric oxide in ethanol at 62 deg with concurrent elimination of nitrogen to afford 2-phenylindane in 75percent yield.Possible rationalizations for these results are presented.

Studies in Antifertility Agents : Part XXXVI-Syntheses of N-(Substituted benzylidene)amino-phthalimides, -dihydroisoindoles and -1,2,3,4-tetrahydroisoquinolines

Syntheses and antifertility activity of a number of N-(substituted benzylidene)amino-phthalimides (3a-i), -dihydroisoindoles (4a-i) and -1,2,3,4-tetrahydroisoquinolines (5a-i) are reported.Some of these compounds prevent pregnancy when administered at 25 mg/kg/day in mice. 100percent abortifacient actvity has been shown by some of these compounds in rats at 20 mg/kg.