374567-13-2

Basic information

• Product Name: (3,4-dihydro-1H-isoquinolin-2-yl)-carbamic acid 4-tert-butoxycarbonylamino-phenyl ester
• Synonyms: (3,4-dihydro-1H-isoquinolin-2-yl)-carbamic acid 4-tert-butoxycarbonylamino-phenyl ester
• CAS NO: 374567-13-2
• Molecular Weight: 383.447
• Mol File: 374567-13-2.mol

Chemical Properties

• CAS DataBase Reference: (3,4-dihydro-1H-isoquinolin-2-yl)-carbamic acid 4-tert-butoxycarbonylamino-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3,4-dihydro-1H-isoquinolin-2-yl)-carbamic acid 4-tert-butoxycarbonylamino-phenyl ester(374567-13-2)
• EPA Substance Registry System: (3,4-dihydro-1H-isoquinolin-2-yl)-carbamic acid 4-tert-butoxycarbonylamino-phenyl ester(374567-13-2)

Safety Data

• Hazardous Substances Data: 374567-13-2(Hazardous Substances Data)

Upstream product

• 4836-98-0 1,2,3,4-tetrahydro-2-amino-isoquinoline 
• 153756-89-9 4-<(tert-butoxycarbonyl)amino>phenyl chloroformate 
• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 54840-15-2 4-N-tert-butoxycarbonylaminophenol 
• 79492-26-5 2-amino-1,2,3,4-tetrahydro-isoquinoline-hydrochloride 

Relevant articles and documents

Carbazates as potent inhibitors of hormone-sensitive lipase

The central role of adipose tissue hormone-sensitive lipase in regulating fatty acid metabolism makes it a potential pharmacological target for the prevention of peripheral insulin resistance in obese, prediabetic and diabetic individuals. The synthesis of a new series of carbazates is presented. Modification of the phenolic 4-position in a series of 1,2,3,4- tetrahydroisoquinoline and morpholine derived carbazates, yielded inhibitors of the catalytic activity of this enzyme with nanomolar potency.

Compounds for treating disorders where a decreased level of plasma FFA is desired

The present invention relates to novel compounds, compositions containing them, and their use for treating medical disorders where a decreased level of plasma free fatty acids (FFA) is desired.