79592-92-0 Usage
Description
23-O-DesMycinosyl-tylosin is a modified tylosin-related macrolide antibiotic that has undergone a chemical modification to remove the mycaminose sugar moiety at the 23-O position. This modification enhances the drug's stability and effectiveness as an antibiotic.
Uses
Used in Pharmaceutical Industry:
23-O-DesMycinosyl-tylosin is used as an orally effective antibiotic for treating bacterial infections. Its modification at the aldehyde functional group allows for improved pharmacokinetics and enhanced efficacy against a range of bacterial pathogens.
Additionally, 23-O-DesMycinosyl-tylosin serves as a degradation product of tylosin macromolecules, which can be further studied and utilized in the development of new antibiotics or understanding the degradation mechanisms of macrolide antibiotics.
Check Digit Verification of cas no
The CAS Registry Mumber 79592-92-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,5,9 and 2 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 79592-92:
(7*7)+(6*9)+(5*5)+(4*9)+(3*2)+(2*9)+(1*2)=190
190 % 10 = 0
So 79592-92-0 is a valid CAS Registry Number.
InChI:InChI=1/C38H63NO13/c1-10-29-26(19-41)15-20(2)11-12-27(42)21(3)16-25(13-14-40)34(22(4)28(43)17-30(44)50-29)52-37-33(45)32(39(8)9)35(23(5)49-37)51-31-18-38(7,47)36(46)24(6)48-31/h11-12,14-15,21-26,28-29,31-37,41,43,45-47H,10,13,16-19H2,1-9H3/b12-11+,20-15+/t21-,22+,23-,24+,25+,26-,28-,29-,31+,32-,33-,34-,35+,36+,37+,38-/m1/s1
79592-92-0Relevant articles and documents
Semisynthetic Macrolide Antibacterials Derived from Tylosin. Synthesis of 23-O-Demycinosyltylosin and Related Compounds
Mallams, Alan K.,Rossman, Randall R.
, p. 775 - 785 (2007/10/02)
The synthesis of a versatile intermediate 4'''-O-(dimethyl-t-butylsilyl)tylosin, directly from tylosin, is described.Its utility in the synthesis of selected acyl derivatives of tylosin, as well in the synthesis of 23-O-demycinosyltylosin, is discussed.Li